Recombinant Human PFN1 Protein, His-tagged PFN1-429H

Cat.No.:	PFN1-429H
Product Overview:	Recombinant Human PFN1(Met1~Gln139) fused with His tag at N-terminal was expressed in E. coli.
Description:	This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
Source:	E. coli
Species:	Human
Tag :	His
Form:	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass:	16.4kDa
Protein length:	Met1~Gln139
Endotoxin:	<1.0EU per 1ug (determined by the LAL method)
Purity:	> 95%
Applications:	Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein
Stability:	The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage:	Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution:	Reconstitute in PBS or others

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Gene Name:	PFN1 profilin 1 [ Homo sapiens ]
Official Symbol:	PFN1
Synonyms:	PFN1; profilin 1; profilin-1; profilin I;
Gene ID:	5216
mRNA Refseq:	NM_005022
Protein Refseq:	NP_005013
MIM:	176610
UniProt ID:	P07737