Active Recombinant Human S100A12 protein, His-tagged
Cat.No. : | S100A12-2563H |
Product Overview : | Active Recombinant Human S100-A12 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Glu92) of human S100A12 (Accession #NP_005612.1) fused with a 6×His tag at the C-terminus. |
- Specification
- Gene Information
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized Human S100A12 at 2 μg/mL (100 μL/well) can bind recombinant Human AGER/RAGE with a linear range of 0.1-27.25 ng/mL. |
Molecular Mass : | 10 kDa |
Protein Length : | Met1-Glu92 |
Endotoxin : | < 0.1 EU/μg of the protein by LAL method. |
Purity : | > 97% by SDS-PAGE. |
Storage : | Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. |
Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |
Gene Name : | S100A12 S100 calcium binding protein A12 [ Homo sapiens ] |
Official Symbol : | S100A12 |
Synonyms : | S100A12; S100 calcium binding protein A12; S100 calcium binding protein A12 (calgranulin C) , S100 calcium binding protein A12 (calgranulin C); protein S100-A12; CAAF1; CAGC; CGRP; ENRAGE; MRP6; p6; EN-RAGE; calgranulin C; calgranulin-C; neutrophil S100 protein; calcium-binding protein in amniotic fluid 1; S100 calcium-binding protein A12 (calgranulin C); extracellular newly identified RAGE-binding protein; |
Gene ID : | 6283 |
mRNA Refseq : | NM_005621 |
Protein Refseq : | NP_005612 |
MIM : | 603112 |
UniProt ID : | P80511 |
Products Types
◆ Recombinant Protein | ||
S100A12-1936H | Recombinant Human S100A12 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A12-3096H | Active Recombinant Human S100A12 protein(Met1-Glu92) | +Inquiry |
S100A12-33H | Recombinant Human S100A12 protein, Myc/DDK-tagged | +Inquiry |
S100A12-2002H | Recombinant Human S100A12 Protein, His-tagged | +Inquiry |
S100A12-063H | Recombinant Human S100A12 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Lysates | ||
S100A12-2094HCL | Recombinant Human S100A12 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionS100A12 regulates the production of pro-inflammatory cytokines, impacting the extent and severity of inflammation.
S100A12 is implicated in inflammatory diseases like rheumatoid arthritis, contributing to joint inflammation and damage.
S100A12 contributes to vascular inflammation, potentially leading to the development of atherosclerosis.
S100A12 plays a role in the innate immune response against bacterial infections, enhancing pathogen detection and response.
Changes in S100A12 expression can exacerbate chronic inflammatory and autoimmune diseases, affecting disease progression and symptoms.
S100A12 influences calcium signaling in immune cells, affecting their activation and function.
S100A12 binds to receptors on immune cells, triggering inflammatory responses and modulating immune activity.
Customer Reviews (3)
Write a reviewPrecise protein quantification, fundamental for data accuracy in our experiments.
Timely antibody validation, a valuable asset for our laboratory.
Exceptional protein expression optimization support, greatly enhances our research.
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