| Cat.No. : | S100A12-2002H |
| Product Overview : | Recombinant Human S100A12 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Glu92) of human S100A12 (Accession #NP_005612.1) fused with a 6×His tag at the C-terminus. |
| Description : | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol. |
| Protein length : | Met1-Glu92 |
| Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Purity : | > 90% as determined by SDS-PAGE |
| Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
| Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
| Gene Name : | S100A12 S100 calcium binding protein A12 [ Homo sapiens (human) ] |
| Official Symbol : | S100A12 |
| Synonyms : | CAAF1;CAGC;CGRP;ENRAGE;MRP-6;MRP6;p6 |
| Gene ID : | 6283 |
| mRNA Refseq : | NM_005621.1 |
| Protein Refseq : | NP_005612.1 |
| MIM : | 603112 |
| UniProt ID : | P80511 |
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