Recombinant Human SMAD1, GST-tagged

Cat.No. : SMAD1-2799H
Product Overview : Recombinant Human SMAD1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Availability July 21, 2024
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
  • Download
Source : E.coli
Species : Human
Tag : GST
Protein length : 19-229aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : SMAD1 SMAD family member 1 [ Homo sapiens ]
Official Symbol : SMAD1
Synonyms : SMAD1; SMAD family member 1; MAD, mothers against decapentaplegic homolog 1 (Drosophila) , MADH1, SMAD, mothers against DPP homolog 1 (Drosophila); mothers against decapentaplegic homolog 1; JV4 1; MADR1; MAD homolog 1; Mad-related protein 1; TGF-beta signaling protein 1; mothers against DPP homolog 1; SMAD, mothers against DPP homolog 1; MAD, mothers against decapentaplegic homolog 1; transforming growth factor-beta signaling protein 1; transforming growth factor-beta-signaling protein 1; BSP1; JV41; BSP-1; JV4-1; MADH1;
Gene ID : 4086
mRNA Refseq : NM_001003688
Protein Refseq : NP_001003688
MIM : 601595
UniProt ID : Q15797
Chromosome Location : 4q31.21
Pathway : ALK1 signaling events, organism-specific biosystem; ALK2 signaling events, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; ErbB1 downstream signaling, organism-s
Function : I-SMAD binding; RNA polymerase II core promoter sequence-specific DNA binding; co-SMAD binding; identical protein binding; protein binding; protein kinase binding; receptor signaling protein activity; sequence-specific DNA binding transcription factor act

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
06/08/2022

    Whether I am investigating enzymatic activity, studying protein-protein interactions, or testing its role in signaling pathways, the SMAD1 protein consistently performs exceptionally well.

    08/08/2021

      This versatility allows me to explore different aspects of my research with confidence and accuracy.

      05/02/2018

        The SMAD1 protein's excellent functionality makes it highly suitable for various trial applications.

        Q&As (5)

        Ask a question
        What technologies are commonly used to study the expression and activity of SMAD1 in clinical research? 04/12/2023

        Techniques like Western blotting, immunohistochemistry, and qRT-PCR are commonly employed to study SMAD1 expression and activity in clinical research.

        How might targeting SMAD1 have implications for anti-cancer therapies? 07/05/2022

        Modulating SMAD1 activity could be explored as a potential strategy for developing anti-cancer therapies, particularly in cancers where the TGF-β pathway is dysregulated.

        Are there any known genetic mutations in the SMAD1 gene associated with human diseases? 03/28/2021

        Yes, mutations in the SMAD1 gene have been identified in certain individuals with congenital disorders and developmental abnormalities.

        How does SMAD1 interact with other proteins in the TGF-β pathway? 01/08/2020

        SMAD1 forms complexes with other SMAD proteins, transducing signals from TGF-β receptors to the nucleus, where they regulate gene expression.

        How can SMAD1 be targeted for therapeutic interventions in bone-related disorders? 12/31/2019

        Targeting SMAD1 or its downstream effectors in the TGF-β pathway may offer potential therapeutic strategies for bone-related disorders, such as osteoporosis.

        Ask a Question for All SMAD1 Products

        Required fields are marked with *

        My Review for All SMAD1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /
        • Service lnquiry:

        Stay Updated on the Latest Bioscience Trends