Recombinant Human SMAD3 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | SMAD3-4788H |
Product Overview : | SMAD3 MS Standard C13 and N15-labeled recombinant protein (NP_005893) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 47.9 kDa |
AA Sequence : | MSSILPFTPPIVKRLLGWKKGEQNG QEEKWCEKAVKSLVKKLKKTGQLDE LEKAITTQNVNTKCITIPRSLDGRL QVSHRKGLPHVIYCRLWRWPDLHSH HELRAMELCEFAFNMKKDEVCVNPY HYQRVETPVLPPVLVPRHTEIPAEF PPLDDYSHSIPENTNFPAGIEPQSN IPETPPPGYLSEDGETSDHQMNHSM DAGSPNLSPNPMSPAHNNLDLQPVT YCEPAFWCSISYYELNQRVGETFHA SQPSMTVDGFTDPSNSERFCLGLLS NVNRNAAVELTRRHIGRGVRLYYIG GEVFAECLSDSAIFVQSPNCNQRYG WHPATVCKIPPGCNLKIFNNQEFAA LLAQSVNQGFEAVYQLTRMCTIRMS FVKGWGAEYRRQTVTSTPCWIELHL NGPLQWLDKVLTQMGSPSIRCSSVS TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | SMAD3 SMAD family member 3 [ Homo sapiens (human) ] |
Official Symbol : | SMAD3 |
Synonyms : | SMAD3; SMAD family member 3; MAD, mothers against decapentaplegic homolog 3 (Drosophila), MADH3, SMAD, mothers against DPP homolog 3 (Drosophila); mothers against decapentaplegic homolog 3; HsT17436; JV15 2; mad3; hMAD-3; hSMAD3; MAD homolog 3; mad homolog JV15-2; mad protein homolog; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD, mothers against DPP homolog 3; MAD, mothers against decapentaplegic homolog 3; LDS1C; MADH3; JV15-2; HSPC193; MGC60396; DKFZp586N0721; DKFZp686J10186; |
Gene ID : | 4088 |
mRNA Refseq : | NM_005902 |
Protein Refseq : | NP_005893 |
MIM : | 603109 |
UniProt ID : | P84022 |
Products Types
◆ Recombinant Protein | ||
Smad3-5951M | Recombinant Mouse Smad3 Protein, Myc/DDK-tagged | +Inquiry |
SMAD3-4147R | Recombinant Rhesus Macaque SMAD3 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMAD3-1918H | Recombinant Human SMAD3 Protein, MYC/DDK-tagged | +Inquiry |
SMAD3-2041H | Recombinant Human SMAD3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Smad3-305M | Recombinant Mouse Smad3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SMAD3-001MCL | Recombinant Mouse SMAD3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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