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Recombinant Human USP13 protein, GST-tagged

Cat.No. : USP13-3616H
Product Overview : Recombinant Human USP13 protein(515-863 aa), fused with GST tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : GST
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH.
Protein Length : 515-863 aa
AA Sequence : IAYELTRREAEANRRPLPELVRAKI PFSACLQAFSEPENVDDFWSSALQA KSAGVKTSRFASFPEYLVVQIKKFT FGLDWVPKKFDVSIDMPDLLDINHL RARGLQPGEEELPDISPPIVIPDDS KDRLMNQLIDPSDIDESSVMQLAEM GFPLEACRKAVYFTGNMGAEVAFNW IIVHMEEPDFAEPLTMPGYGGAASA GASVFGASGLDNQPPEEIVAIITSM GFQRNQAIQALRATNNNLERALDWI FSHPEFEEDSDFVIEMENNANANII SEAKPEGPRVKDGSGTYELFAFISH MGTSTMSGHYICHIKKEGRWVIYND HKVCASERPPKDLGYMYFYRRIPS
Purity : 85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) [ Homo sapiens ]
Official Symbol : USP13
Synonyms : USP13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T 3); ubiquitin carboxyl-terminal hydrolase 13; IsoT 3; isopeptidase T-3; ubiquitin thioesterase 13; deubiquitinating enzyme 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13; ubiquitin specific protease 13 (isopeptidase T-3); ISOT3; IsoT-3;
Gene ID : 8975
mRNA Refseq : NM_003940
Protein Refseq : NP_003931
MIM : 603591
UniProt ID : Q92995

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can USP13 be a potential therapeutic target for neurodegenerative diseases? 02/09/2022

There is emerging research suggesting that USP13 may play a role in neurodegenerative diseases, and targeting it could be a potential avenue for therapeutic intervention.

How does USP13 interact with other proteins in cellular pathways? 07/26/2021

USP13 interacts with various proteins, forming complexes that regulate different cellular pathways. Understanding these interactions is crucial for deciphering its role in health and disease.

Are there any known genetic variations in the USP13 gene associated with disease susceptibility? 02/17/2021

Genetic variations in the USP13 gene have been studied, and certain polymorphisms may be associated with an increased risk of specific diseases. Further research is ongoing in this area.

In what other medical conditions is USP13 protein being investigated? 03/22/2019

Researchers are exploring the role of USP13 in neurodegenerative diseases, inflammatory disorders, and other conditions where ubiquitin-mediated processes play a crucial role.

How does USP13 influence cellular response to stress and DNA damage? 04/03/2016

USP13 has been found to regulate the stability of proteins involved in the DNA damage response, affecting how cells respond to stress and maintain genomic integrity.

Customer Reviews (3)

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Reviews
01/02/2023

    Its purity, integrity, and consistency ensure reliable and reproducible results, which are essential for meaningful scientific discoveries.

    06/29/2016

      Their in-depth understanding of the protein's characteristics, applications, and potential limitations allows for valuable insights and recommendations, ensuring the success of my experiments.

      04/07/2016

        Whether it's troubleshooting, protocol optimization, or general inquiries, their knowledgeable and responsive team is readily available to assist and solve any problems that may arise during the experimental process.

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