Cat.No. : |
VTN-062H
Optional Service: Optional requirements on this protein
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Product Overview : |
Recombinant human Vitronectin / VTN (rhVitronectin) Asp20-Leu478 (Accession # NP_000629.3 ) fused with a N-terminal 6×His tag was produced in human HEK 293 cells. |
Description : |
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008] |
Source : |
HEK293 cells |
Species : |
Human |
Tag : |
His |
Molecular Mass : |
rhVitronectin is fused with a 6×his tag at N-terminal and the protein has a calculated MW of 53 kDa. DTT- reduced protein migrates as 66-70 kDa in SDS-PAGE resulting from glycosylation. |
Endotoxin : |
Less than 1.0 EU per 1 µg of the rhVitronectin by the LAL method. |
Purity : |
>90% as determined by SDS-PAGE. All lots are greater than 90% pure. |
Notes : |
Research Use Only. Not for use in diagnostic or therapeutic procedures. |
Storage : |
Store at -20 centigrade in lyophilized state after receipt. For long term storage, upon reconstitution rhTNFa should be aliquot and store at -20 centigrade or -8 centigrade centigrade. Avoid repeated freeze-thaw cycles. |
Storage Buffer : |
Bulk protein in a 0.22 µm filtered solution of PBS, pH 7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization. |