Recombinant Mouse Cryaa Protein, Myc/DDK-tagged

• Cat.No.: Cryaa-2325M
• Product Overview: Purified recombinant protein of mouse full-length crystallin, alpha A (cDNA clone MGC:106604 IMAGE:30602480), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes subunit a, one of two subunits of alpha-crystallin, which is a high molecular weight, soluble aggregate and is a member of the small heat shock protein (sHSP) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. It acts as a molecular chaperone and is the major protein in the eye lens, maintaining the transparency and refractive index of the lens. In mouse, deficiency in this gene is associated with smaller lenses and eyes and with increasing lens opacity with age. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 19.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cryaa crystallin, alpha A [ Mus musculus (house mouse) ]
• Official Symbol: Cryaa
• Synonyms: Cryaa; crystallin, alpha A; Cry; Acry; Crya; Crya1; DAcry; lop18; Acry-1; Crya-1; DAcry-1; alpha-crystallin A chain; crystallin, alpha 1; lens opacity 18
• Gene ID: 12954
• mRNA Refseq: NM_013501
• Protein Refseq: NP_038529
• UniProt ID: P24622