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Active Recombinant Mouse Cxcl2 Protein (73 aa)

Cat.No. : Cxcl2-328C
Product Overview : Recombinant mouse MIP-2/CXCL2 produced in E. coli is a single non-glycosylated polypeptide chain containing 73 amino acids. A fully biologically active molecule, rmMIP-2/CXCL2 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
  • Specification
  • Gene Information
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Description : Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence to a related chemokine, CXCL1. CXCL2 is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. CXCL2 can signal through the CXCR2 receptor.
Source : E. coli
Species : Mouse
Form : Sterile Filtered White lyophilized (freeze-dried) powder.
Bio-activity : The EC50 value of mouse MIP-2/CXCL2 on Ca^2+ mobilization assay in CHO-K1/Gα15/mCXCR2 cells (human Gα15 and mouse CXCR2 stably expressed in CHO-K1 cells) is less than 1 ng/mL.
Molecular Mass : 8.0 kDa, observed by reducing SDS-PAGE.
Protein Length : 73
AA Sequence : GAVVASELRCQCLKTLPRVDFKNIQ SLSVTPPGPHCAQTEVIATLKGGQK VCLDPEAPLVQKIIQKILNKGKAN
Endotoxin : < 0.2 EU/μg, determined by LAL method.
Purity : > 95% as analyzed by SDS-PAGE.
Storage : Lyophilized recombinant mouse MIP-2/CXCL2 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, mouse MIP-2/CXCL2 should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade.
Storage Buffer : Lyophilized after extensive dialysis against PBS.
Reconstitution : Reconstituted in ddH2O or PBS at 100 μg/mL.
Gene Name : Cxcl2 chemokine (C-X-C motif) ligand 2 [ Mus musculus ]
Official Symbol : Cxcl2
Synonyms : CXCL2; chemokine (C-X-C motif) ligand 2; C-X-C motif chemokine 2; macrophage inflammatory protein 2; small inducible cytokine subfamily, member 2; GROb; Gro2; Mip2; Scyb; MIP-2; Scyb2; MIP-2a; Mgsa-b; CINC-2a;
Gene ID : 20310
mRNA Refseq : NM_009140
Protein Refseq : NP_033166
UniProt ID : P10889

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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