Cxcl2

  • Official Full Name

    chemokine (C-X-C motif) ligand 2

  • Overview

    Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.
  • Synonyms

    GROb; Gro2; Mip2; Scyb; MIP-2; Scyb2; MIP-2a; Mgsa-b; CINC-2a; Cxcl2; chemokine (C-X-C motif) ligand 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • ELISA Kit
  • Protein Pre-coupled Magnetic Beads
  • Cotton Rat
  • Horse
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Human Cell
  • Human Cells
  • Human Pleural Fluid
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • yeast
  • Yeast
  • Biotin
  • C
  • His
  • DYKDDDDK
  • GST
  • His (Fc)
  • Avi
  • SUMO
  • His|Flag|StrepII
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CXCL2-17H Active Recombinant Human CXCL2 yeast N/A
Human CXCL2-476H Recombinant Human CXCL2 protein E.coli N/A 73
Human CXCL2-2165P Active Recombinant CXCL2 Protein, His-Flag-StrepII-tagged Human Cell His/Flag/StrepII
Human CXCL2-282H Recombinant Human CXCL2, StrepII-tagged Human Cell Strep II 35-107, 73 a.a.
Human CXCL2-2167H Recombinant Human CXCL2 Protein, GST-tagged Wheat Germ GST
Human CXCL2-224H Recombinant Human chemokine (C-X-C motif) ligand 2, His-tagged Human His
Human CXCL2-7168HCL Recombinant Human CXCL2 293 Cell Lysate HEK293 N/A
Human CKERS-CXCL2-019H Human CXCL2 ELISA Kit Human Pleural Fluid N/A
Human CXCL2-401H Recombinant Human CXCL2 Protein (Ala35-Asn107) E.coli N/A Ala35-Asn107
Human CXCL2-1426H Recombinant Human CXCL2 protein, His-GST & Myc-tagged E.coli His-GST & Myc 35-107aa
Human CXCL2-3982H Recombinant Human CXCL2 Protein, MYC/DDK-tagged HEK293T Myc/DDK
Human CXCL2-135H Active Recombinant Human CXCL2 Protein (Ala35-Asn107), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala35-Asn107
Human CXCL2-1930H Recombinant Human CXCL2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CXCL2-03H Recombinant Human CXCL2 Protein E.coli 73 amino acid
Human CXCL2-121H Recombinant Human CXCL2 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CXCL2-14H Recombinant Human CXCL2 Protein, Biotin-tagged E.coli Biotin
Human CXCL2-2287HF Recombinant Full Length Human CXCL2 Protein, GST-tagged In Vitro Cell Free System GST 107 amino acids
Human CXCL2-64H Active Recombinant Human CXCL2 Protein E.coli
Human CXCL2-2100H Recombinant Human CXCL2 Protein (Thr39-Asn107), C-His tagged E.coli C-His Thr39-Asn107
Human CXCL2-388C Active Recombinant Human CXCL2 Protein (74 aa) E.coli 74
Human CXCL2-2101H Recombinant Human CXCL2 Protein (Gly34-Asn107), N-His tagged E.coli N-His Gly34-Asn107
Mouse Cxcl2-13M Active Recombinant Mouse Cxcl2 yeast N/A
Mouse Cxcl2-01M Active GMP Recombinant Mouse Cxcl2 Protein, His-Tagged E.coli His
Mouse Cxcl2-428M Recombinant Mouse Cxcl2 protein(Ala28-Asn100), His-tagged Yeast C-His Ala28-Asn100
Mouse Cxcl2-200M Recombinant Mouse Cxcl2 protein, His&SUMO-tagged E.coli His&SUMO Ala28-Asn100
Mouse Cxcl2-2169M Recombinant Mouse Cxcl2 protein E.coli N/A 73
Mouse Cxcl2-38M Recombinant Mouse Chemokine (C-X-C Motif) Ligand 2 E.coli His
Mouse CXCL2-4105M Recombinant Mouse CXCL2 Protein Mammalian Cell His
Mouse CXCL2-2097M-B Recombinant Mouse CXCL2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cxcl2-2395M Active Recombinant Mouse Cxcl2 Protein E. coli
Mouse Cxcl2-3390M Recombinant Mouse Cxcl2 Protein E.coli N/A
Mouse CXCL2-65M Active Recombinant Mouse CXCL2 Protein E.coli
Mouse Cxcl2-020C Active Recombinant Mouse Cxcl2 Protein (73 aa) E.coli 73
Mouse Cxcl2-2396M Active Recombinant Mouse Cxcl2 Protein E. coli Ala28-Asn100
Mouse Cxcl2-78M Active Recombinant Mouse Cxcl2 Protein (Ala28-Asn110), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala28-Asn110
Mouse Cxcl2-328C Active Recombinant Mouse Cxcl2 Protein (73 aa) E.coli 73
Mouse Cxcl2-5249M Recombinant Mouse Cxcl2 protein, His-tagged E.coli His 28-100aa
Mouse CXCL2-2097M Recombinant Mouse CXCL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cxcl2-626R Active Recombinant Rat Cxcl2 E.coli N/A
Rat Cxcl2-578R Recombinant Rat Cxcl2 protein, His & GST-tagged E.coli His/GST Ser32~Asn100
Rat CXCL2-1689R Recombinant Rat CXCL2 Protein Mammalian Cell His
Rat Cxcl2-54R Recombinant Rat Cxcl2 protein E.coli N/A 73
Rat Cxcl2-1070R Recombinant Rat Cxcl2 protein E.coli N/A Ser32-Asn100
Rat Cxcl2-010C Active Recombinant Rat Cxcl2 Protein (73 aa) E.coli 73
Rat Cxcl2-386C Active Recombinant Rat Cxcl2 Protein (73 aa) E.coli 73
Rat CXCL2-1348R Recombinant Rat CXCL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cxcl2-387C Active Recombinant Rat Cxcl2 Protein (69 aa) E.coli 69
Rat CXCL2-1348R-B Recombinant Rat CXCL2 Protein Pre-coupled Magnetic Beads HEK293
Cotton Rat Cxcl2-395C Active Recombinant Cotton Rat Cxcl2 E.coli N/A
Horse CXCL2-885H Recombinant Horse CXCL2 Protein, His-tagged E.coli N-His Ala35-Asp107
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Cxcl2 Related Articles
  • Cxcl2 Related Gene Family
  • Cxcl2 Related Research Area

Cxcl2 involved in several pathways and played different roles in them. We selected most pathways Cxcl2 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cxcl2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL29;CTF1;IFNA21;CCR7;TNFSF4;IL26;CCL3;PF4;CCL8
Chemokine signaling pathwayDOCK2;GNG4;AKT1;RHOA;CCL3L3;ARRB1;SRC;CCL22;ADRBK2
NF-kappa B signaling pathwayTNFRSF11A;IRAK1;TRAF3;Bcl2a1b;ZAP70;XIAP;BLNK;LCK;TRAF2
NOD-like receptor signaling pathwayCASPA;NLRP3;MAPK8A;MAPK11;CARD8;PSTPIP1A;RIPK2;NAIP6;MAPK13
TNF signaling pathwayCREB5;LTA;PIK3R5;CASP7;MAP3K7IP3;CREB3L2;BAG4;AKT1;MMP3
Salmonella infectionRILP;WASL;TLR4BB;PFN1;CCL3L3;CCL4;ROCK2B;CXCL8B.3;CCL4L2
LegionellosisCASP8;IL12A;TLR2;HSPA6;BCL2L13;ITGAM;CXCL2;CXCL1;NFKB1

Cxcl2 has several biochemical functions, for example, CXCR chemokine receptor binding, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cxcl2 itself. We selected most functions Cxcl2 had, and list some proteins which have the same functions with Cxcl2. You can find most of the proteins on our site.

Function Related Protein
CXCR chemokine receptor bindingIL8L2;CXCL1;AMCF-II;PF4V1;ITCH;CXCL18B;CXCL5;PPBP;CXCL2
chemokine activityCcl21a;CXCL5;CXCL16;Cxcl15;CCL15;CCL26;CCL21;PF4;CXCL19
protein bindingARSA;WDR12;SMN2;C6;PDIA4;PRPSAP1;PCMT1;PDIK1L;WEE1

Cxcl2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cxcl2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cxcl2.

DPP4; EPS8; PIK3R5

Maeda, A; Bandow, K; et al. Induction of CXCL2 and CCL2 by pressure force requires IL-1 beta-MyD88 axis in osteoblasts. BONE 74:76-82(2015).
McDermott, AJ; Higdon, KE; et al. The role of Gr-1(+) cells and tumour necrosis factor-alpha signalling during Clostridium difficile colitis in mice. IMMUNOLOGY 144:704-716(2015).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Cxcl2 Products

Required fields are marked with *

My Review for All Cxcl2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends