Recombinant Mouse Fgf21 Protein, Myc/DDK-tagged
Cat.No. : | Fgf21-2997M |
Product Overview : | Purified recombinant protein of mouse full-length fibroblast growth factor 21 (Fgf21), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc&DDK |
Molecular Mass : | 23.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Fgf21 fibroblast growth factor 21 [ Mus musculus (house mouse) ] |
Official Symbol : | Fgf21 |
Synonyms : | FGF21; fibroblast growth factor 21; FGF-21 |
Gene ID : | 56636 |
mRNA Refseq : | NM_020013 |
Protein Refseq : | NP_064397 |
UniProt ID : | Q9JJN1 |
Products Types
◆ Recombinant Protein | ||
FGF21-034H | Active Recombinant Human FGF21 Protein | +Inquiry |
FGF21-1966H | Recombinant Human FGF21 Protein, MYC/DDK-tagged | +Inquiry |
Fgf21-1490R | Recombinant Rat Fgf21 Protein, His-tagged | +Inquiry |
FGF21-120F | Active Recombinant Human FGF21 Protein (182 aa) | +Inquiry |
FGF21-1567H | Recombinant Human FGF21 protein, mFc-Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
FGF21-1890MCL | Recombinant Mouse FGF21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe manufacturer's history of producing high-quality products contributed to our trust in this protein.
Collaboration with other research groups was made easier by the product's standardized use in the scientific community.
The product's role in promoting collaboration and teamwork positively impacted the quality of our research.
Q&As (7)
Ask a questionFGF21 expression in adipose tissue is regulated by various factors, including peroxisome proliferator-activated receptor gamma (PPARγ) activation.
FGF21 influences lipid metabolism by promoting the utilization of fatty acids for energy, contributing to the regulation of lipid homeostasis.
FGF21 levels are being explored as potential biomarkers for metabolic health, reflecting conditions such as insulin resistance and metabolic syndrome.
Yes, FGF21 plays a role in improving insulin sensitivity, making it a potential target for interventions in insulin resistance-associated conditions.
Yes, FGF21 influences energy expenditure by promoting thermogenesis in brown adipose tissue, contributing to overall metabolic regulation.
Gender-specific differences in FGF21 levels have been reported, with some studies suggesting higher circulating FGF21 concentrations in females.
FGF21 activates signaling pathways such as the AMP-activated protein kinase (AMPK) pathway, which contributes to its metabolic effects.
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