fgf21

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fgf21

Official Full Name fibroblast growth factor 21
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq, Jul 2008]
Synonyms FGF21; fibroblast growth factor 21;
    • Species :
    • Bovine
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Bovine
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • Flag
    • GST
    • His
    • S
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF21-103H Recombinant Human Fibroblast Growth Factor 21 E.coli N/A
    Human FGF21-104H Recombinant Human FGF21, His-tagged E.coli His
    Human FGF21-133H Recombinant Human FGF21 Protein, His-tagged E.coli His
    Human FGF21-192H Recombinant Human FGF21 protein, His/S-tagged E.coli His/S
    Human FGF21-1966H Recombinant Human FGF21 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FGF21-28827TH Recombinant Human FGF21, His-tagged HEK293 His
    Human FGF21-28828TH Recombinant Human FGF21, FLAG-tagged HEK293 Flag
    Human FGF21-28829TH Recombinant Human FGF21, Fc-tagged HEK293 Fc
    Human FGF21-4111H Recombinant Human FGF21 Protein, GST-tagged Wheat Germ GST
    Human FGF21-562H Recombinant Human FGF21 protein E.coli N/A
    Human FGF21-564H Recombinant Human FGF21, His tagged E.coli His
    Mouse Fgf21-109M Recombinant Mouse Fibroblast Growth Factor 21 E.coli N/A
    Mouse Fgf21-110M Recombinant Mouse Fibroblast Growth Factor 21, His-tagged E.coli His
    Mouse FGF21-1890MCL Recombinant Mouse FGF21 cell lysate Human Cell N/A
    Mouse Fgf21-193M Recombinant Mouse Fgf21 protein, His/S-tagged E.coli His/S
    Mouse Fgf21-256M Recombinant Mouse Fgf21, FLAG-tagged HEK293 Flag
    Mouse Fgf21-258M Recombinant Mouse Fgf21, Fc-tagged HEK293 Fc
    Mouse FGF21-36M Recombinant Mouse FGF21 Protein, His-tagged Insect Cell His
    Mouse Fgf21-414M Recombinant Mouse Fibroblast Growth Factor 21, FLAG-tagged Human Cell Flag
    Mouse Fgf21-503M Recombinant Mouse Fgf21, His-tagged E.coli HIS
    Mouse Fgf21-504M Recombinant Mouse Fgf21 E.coli His
    Mouse Fgf21-563M Recombinant Mouse Fgf21 protein E.coli N/A
    Mouse Fgf21-574M Recombinant Mouse Fgf21, His tagged Human Cell His
    Rat Fgf21-194R Recombinant Rat Pdgfa protein, His/S-tagged E.coli His/S
    Rat Fgf21-589R Recombinant Rat Fgf21 protein E.coli N/A
    Cynomolgus Monkey FGF21-1236C Recombinant Cynomolgus FGF21 Protein, His-tagged HEK293 His
    Bovine FGF21-626B Recombinant Bovine Fibroblast Growth Factor 21 Bovine N/A
    Zebrafish FGF21-4310Z Recombinant Zebrafish FGF21 Mammalian Cell His

    fgf21 involved in several pathways and played different roles in them. We selected most pathways fgf21 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with fgf21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway MRAS; TRAF6; CACNA2D4; FGF22; PPP3CCA; CACNA2D2; CACNA1D; PPP3R2; PPM1NB; MAP2K1
    Ras signaling pathway RALB; ANGPT4; KRAS; ARF6; RAPGEF5; PLA1A; Kitl; PIK3R2; FGF16; KLK1B4
    Rap signaling pathway ITGB2L; FGFR2; RAC3; FGFR1; THBS1; TEK; ITGA2B; FGF11; KLK1B4; FGF19
    PIK-Akt signaling pathway PPP2R5C; PRLR; LAMB3; RBL2; INSR; PPP2R3C; LPAR2; PDGFA; IGF1; PPP2R2B
    Regulation of actin cytoskeleton FGF6A; Itgam&Itgb2; MYL12.2; RAC1; HRASB; ROCK2B; DIAPH1; FGF13A; RAC2; ITGA10
    Pathways in cancer AXIN1; NCOA4; ITGA2; GNG12; ARHGEF1; Shh; FZD6; CSF3R; LAMA3; TRAF3
    Melanoma FGF22; PDGFC; MAP2K1; FGF7; FGF8; FGF6; PDGFRB; FGFR1; MAPK1; FGF2

    fgf21 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fgf21 itself. We selected most functions fgf21 had, and list some proteins which have the same functions with fgf21. You can find most of the proteins on our site.

    Function Related Protein
    fibroblast growth factor receptor binding FGF6; FGF1; FGF20A; FRS3; FGF20B; FGF18A; FGF22; FGF6A; FGF18B; FGF8
    growth factor activity GDF10B; RABEP1; FGF10B; AMELX; BMP7A; BMP1; FGF22; MSTNA; MDKA; GDF15
    protein binding CDC42BPA; TAF12; MYBPC3; C9orf100; NLGN4Y; FOXR2; PPP2R5A; RHOH; CUL4B; SKAP2

    fgf21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fgf21 here. Most of them are supplied by our site. Hope this information will be useful for your research of fgf21.

    KLB; CDC25A; MAPK7; TNS2; CDH7

    Zhang, J; Li, Y; et al. Fibroblast growth factor 21, the endocrine FGF pathway and novel treatments for metabolic syndrome. DRUG DISCOVERY TODAY 19:579-589(2014).
    Umberger, TS; Sloan, JH; et al. Novel sandwich immunoassays for the measurement of total and active FGF21. BIOANALYSIS 6:3283-3293(2014).

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