Description : |
Interleukin-7 (IL-7), also known as lymphopoietin 1 and pre-B cell factor, is a hematopoietic growth factor belonging to the IL-7/IL-9 family. It is produced by keratinocytes, dendritic cells, hepatocytes, neurons and epithelial cells. IL-7 binds and signals through IL-7 receptor,a heterodimer consisting of IL-7 receptor alpha and common gamma chain receptor.IL-7 plays a role in regulating early B cell and T cell development. It is also important for optimal dendritic cell-T cell interaction. |
Source : |
CHO |
Species : |
Mouse |
Tag : |
His |
Form : |
Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : |
ED50< 0.4 ng/mL, measured in a cell proliferation assay using 2E8 cells. |
Molecular Mass : |
8-28kDa, observed by reducing SDS-PAGE. |
AA Sequence : |
ECHIKDKEGKAYESVLMISIDELDK MTGTDSNCPNNEPNFFRKHVCDDTK EAAFLNRAARKLKQFLKMNISEEFN VHLLTVSQGTQTLVNCTSKEEKNVK EQKKNDACFLKRLLREIKTCWNKIL KGSIHHHHHH |
Endotoxin : |
< 0.2 EU/μg, determined by LAL method. |
Purity : |
> 95% as analyzed by SDS-PAGE. |
Storage : |
Lyophilized recombinant murine Interleukin-7 (IL-7), His remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, murine Interleukin-7 (IL-7), His should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : |
Lyophilized after extensive dialysis against PBS. |
Reconstitution : |
Reconstituted in ddH2O or PBS at 100 μg/mL. |