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Active Recombinant Human IL7 Full Length protein, His tagged

Cat.No. : IL7-507H
Product Overview : Recombinant Human IL7 protein(Asp26-His177), fused with C-terminal His tag, was expressed in HEK293.
Availability February 15, 2025
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Source : HEK293
Species : Human
Tag : C-His
Protein length : Asp26-His177
Form : Lyophilized from sterile PBS, pH7.4, 5% trehalose, 5% mannitol.
Bio-activity : Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 142.2 pg/mL.
Molecular Mass : The protein has a calculated MW of 18.2kDa, and migrates as an approximately 19-30kDa band in SDS-PAGE under reducing conditions.
AASequence : DCDIEGKDGKQYESVLMVSIDQLLD SMKEIGSNCLNNEFNFFKRHICDAN KEGMFLFRAARKLRQFLKMNSTGDF DLHLLKVSEGTTILLNCTGQVKGRK PAALGEAQPTKSLEENKSLKEQKKL NDLCFLKRLLQEIKTCWNKILMGTK EHHHHHHH
Endotoxin : <1.0EU per 1μg (determined by the LAL method).
Purity : > 90 % as determined by SDS-PAGE.
Storage : Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.3 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL7 interleukin 7 [ Homo sapiens ]
Official Symbol : IL7
Synonyms : IL7; interleukin 7; interleukin-7; IL 7; IL-7;
Gene ID : 3574
mRNA Refseq : NM_000880
Protein Refseq : NP_000871
MIM : 146660
UniProt ID : P13232

Not For Human Consumption!

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Reviews
03/27/2022

    Effective in signal transduction pathway.

    04/17/2021

      IL7 has good absorbability and high bioavailability.

      11/27/2020

        Good stability under different environmental conditions

        Q&As (6)

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        What are the application scenarios of IL7? 10/10/2020

        IL7 is widely used in the research and development of immunotherapy protocols, can enhance the body's immune function, for the treatment of cancer, infection, autoimmune diseases and other diseases.

        What is the mechanism of IL7 in the treatment of bladder cancer? 11/25/2019

        IL7 can activate the body's immune system and enhance the immune cells' attack on bladder cancer.

        What is the optimal dose of IL7 in the treatment of leukemia? 07/18/2019

        The dosage of IL7 in the treatment of leukemia needs to be calculated individually according to the specific situation of the patient.

        Does the efficacy of IL7 in the treatment of infectious diseases? 04/10/2019

        It can enhance the function of the body's immune system, and has a certain effect on some infectious diseases.

        Are there have any efficacy of IL7 in the treatment of specific cancers? 03/31/2019

        Recombinant IL7 protein may have some therapeutic effect on specific cancers by activating T cells, but further clinical studies are needed.

        How to prepare IL7? 03/27/2019

        This is obtained by recombinant DNA technology, inserting foreign genes into the host expression system, and then through purification and other steps.

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