Il7

  • Official Full Name

    interleukin 7

  • Overview

    Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by normal lymphocytes.
  • Synonyms

    IL7; Interleukin 7; IL-7; interleukin 7;

  • Recombinant Proteins
  • GMP Proteins
  • Cell & Tissue Lysates
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Chicken
  • Human
  • Mouse
  • Rabbit
  • Rat
  • Rhesus Macaque
  • CHO
  • CHO-K1
  • E.coli
  • HEK293
  • HEK293F
  • Hordeum Vulgare
  • Human Cell
  • Human cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Nicotiana Benthamiana
  • S.cerevisiae
  • Wheat Germ
  • C
  • His
  • Fc
  • GST
  • hFc
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • SUMO
  • HQ
  • Met
  • N/A
  • N
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL7-67H Active Recombinant Human Interleukin 7, His tagged, Animal Free Nicotiana Benthamiana His
Human IL7-507H Active Recombinant Human IL7, His tagged Human Cell His
Human IL7-9011H Active Recombinant Human IL7 E.coli N/A
Human IL7-032E Active Recombinant Human IL7 protein(Asp26-His177) E.coli N/A Asp26-His177
Human IL7-506H Active Recombinant Human IL7 protein HEK293 N/A Asp 26 - His 177
Human IL7-146H Active Recombinant Human IL7 protein E.coli N/A
Human IL7-01HG Active GMP Recombinant Human IL7 Protein CHO-K1
Human IL7-115HG Active GMP Recombinant Human IL7 Protein E.coli
Human IL7-14210H Recombinant Human IL7, His-tagged E.coli His 1-177a.a.
Human IL7-5333H Recombinant Human Interleukin 7, HQ-tagged Hordeum Vulgare HQ
Human IL7-64H Recombinant Human IL7 protein E.coli N/A 152
Human IL7-65H Recombinant Human IL7, His-tagged E.coli His
Human IL7-572H Recombinant Human IL7 E.coli N/A
Human IL7-51H Active Recombinant Human Interleukin 7, MIgG2a Fc-tagged CHO Fc
Human IL7-1559H Recombinant human IL7, Active, His-tagged Nicotiana Benthamiana His
Human IL7-271H Recombinant Human IL7, StrepII-tagged Human Cell Strep II 36-177, 142 a.a.
Human IL7-52H Active Recombinant Human Interleukin 7, HIgG1 Fc-tagged CHO Fc
Human IL7-53H Active Recombinant Human Interleukin 7, HIgG1 Fc-tagged, mutant CHO Fc
Human IL7-233H Recombinant Human IL7 Mammalian Cell His
Human IL7-66H Recombinant Human Interleukin 7, 152aa S.cerevisiae N/A
Human IL7-29H Recombinant Human IL7 protein, His-tagged Insect Cell His
Human IL7-5223HCL Recombinant Human IL7 293 Cell Lysate HEK293 N/A
Human IL7-55H Recombinant Human IL7 Protein, His-tagged HEK293 His
Human IL7-03HG Active Recombinant Human IL7 Protein (Asp26-His177), GMP Grade, Animal-Free E.coli Asp26-His177
Human IL7-215H Recombinant Human IL7 Protein, His-tagged(C-ter) HEK293 His(C-ter) Asp26-His177
Human IL7-2576H Recombinant Human IL7 Protein (Asp26-His177), C-His tagged E.coli C-His Asp26-His177
Human IL7-152HG Active GMP Recombinant Human IL7 protein CHO
Human IL7-234I Active Recombinant Human IL7 Protein, His-tagged CHO His
Human IL7-187H Active Recombinant Human IL7 Protein E.coli
Human IL7-069H Active Recombinant Human IL7 Protein E.coli
Human IL7-2380H Recombinant Human IL7 protein, His-SUMO-tagged E.coli His-SUMO 26-177aa
Human IL7-23HG Active Recombinant Human IL7 Protein (Asp26-His177), GMP Grade, Animal-Free E.coli Asp26-His177
Human IL7-092I Active Recombinant Human IL7 Protein (153 aa) E.coli 153
Human IL7-38H Active Recombinant Human IL7 Protein, Animal Free Human cells
Human IL7-4322HG GMP Recombinant Human IL7 protein E.coli N/A 152
Human IL7-102H Human Interleukin-7 (rDNA derived) Reference standard N/A
Human IL7-1056H Recombinant Human IL7 Protein, His-tagged HEK293F N-His Asp26-His177
Human IL7-121H Recombinant Human IL7 Protein, His-tagged Human Cell His Asp26-His177
Human IL7-151HG Active GMP Recombinant Human IL7 Protein HEK293
Human IL7-5170H Recombinant Human IL7 Protein, GST-tagged Wheat Germ GST
Human IL7-0190H Active Recombinant Human IL7 protein, Fc-tagged HEK293 Fc Asp26-His177
Human IL7-3155H Recombinant Human IL7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IL7-34HG Recombinant Human IL7 Protein, GMP Grade, Animal-Free E.coli 152 amino acid
Human IL7-22H Recombinant Human IL7 Protein, His-tagged Insect Cell His
Human IL7-171H Active Recombinant Human IL7 Protein (Asp26-His177), C-His tagged, Animal-free, Carrier-free E.coli C-His Asp26-His177
Human IL7-495H Active Recombinant Human IL7 protein, hFc-tagged HEK293 hFc Met1-His177
Human IL7-232H Recombinant Human IL7 protein HEK293 N/A Asp26-His177
Human IL7-518H Recombinant Human IL7 Protein 177
Human IL7-5695HF Recombinant Full Length Human IL7 Protein, GST-tagged In Vitro Cell Free System GST 26-177 amino acids
Human IL7-3155H-B Recombinant Human IL7 Protein Pre-coupled Magnetic Beads HEK293
Human IL7-214H Recombinant Active Human IL7 Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse Il7-475M Active Recombinant Mouse Interleukin 7 E.coli N/A
Mouse Il7-01M Active Recombinant Mouse Il7 Protein, His-Tagged E.coli His
Mouse Il7-767M Active Recombinant Mouse Il7 protein E.coli N/A Glu26-Ile154
Mouse Il7-77M Recombinant Mouse Il7 protein E.coli N/A 129
Mouse Il7-742M Recombinant Mouse Il7 protein, His-tagged E.coli His Glu26~Ile154 (Accession # P10168)
Mouse Il7-62M Active Recombinant Mouse Il7 Protein (Glu26-Ile154), C-His tagged, Animal-free, Carrier-free E.coli C-His Glu26-Ile154
Mouse Il7-233I Active Recombinant Mouse Il7 Protein, His-tagged CHO His
Mouse Il7-216M Recombinant Active Mouse IL7 Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse Il7-137M Mouse Interleukin-7 (rDNA derived) Reference standard N/A
Mouse Il7-117M Active Recombinant Mouse Il7 Protein E.coli
Mouse Il7-1683M Recombinant Mouse Il7 Protein, His-tagged E.coli N-His Met1-Ile154
Mouse IL7-188M Active Recombinant Mouse IL7 Protein E.coli
Mouse Il7-118M Active Recombinant Mouse Il7 Protein Insect Cell
Mouse IL7-218M Recombinant Mouse IL7 Protein, His-tagged Human Cell His
Mouse IL7-0189M Active Recombinant Mouse IL7 protein, His-tagged HEK293 His Glu26-Ile154
Mouse IL7-2172M Recombinant Mouse IL7 Protein Insect Cell N/A
Rat Il7-670R Active Recombinant Rat Il7 E.coli Met Asp26-Ile154
Rat Il7-174R Recombinant Rat Interleukin 7 E.coli N/A
Rat Il7-578R Recombinant Rat Il7 protein E.coli N/A 129
Rat Il7-0299R Active Recombinant Rat Il7 protein E.coli N/A Asp26-Ile154
Rat Il7-232I Active Recombinant Rat Il7 Protein, His-tagged CHO His
Rat Il7-1684R Recombinant Rat Il7 Protein, His-tagged E.coli N-His His28-Asn151
Rabbit IL7-743R Recombinant Rabbit IL7 protein, His-tagged E.coli His Asn26~Asn159
Bovine IL7-1371B Recombinant Bovine IL7 protein, His-tagged E.coli His 26-176aa
Rhesus Macaque IL7-2256R Recombinant Rhesus monkey IL7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque IL7-2077R-B Recombinant Rhesus Macaque IL7 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque IL7-2077R Recombinant Rhesus Macaque IL7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken IL7-01C Recombinant Chicken IL7 Protein, His-tagged E.coli His
Chicken IL7-3302C Recombinant Chicken IL7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

Il7 involved in several pathways and played different roles in them. We selected most pathways Il7 participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionOSM;IL12A;KDRL;GM13304;HGF;TNFRSF9;EPOR;IL15RA;IFNA10
PIK-Akt signaling pathwayFN1;IL6R;NGFR;Il4ra;COL6A6;VEGFC;IBSP;MCL1;THBS4
Jak-STAT signaling pathwaySTAT1;BCL2;FHL1;IL11;CTF1;Gh;PRL;PIK3CA;M17
Hematopoietic cell lineageCD8B;CD37;FCGR1;IL7R;IL5RA;IL11;THPO;ITGA1;HLA-DRB5

Il7 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-7 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il7 itself. We selected most functions Il7 had, and list some proteins which have the same functions with Il7. You can find most of the proteins on our site.

Function Related Protein
cytokine activityIL34;CER1;BMP5;GM13278;TGFB1A;LFT1;GDF6;NDP;IFNPHI4
growth factor activityCSF1A;FGF10;FGF6;GDF11;SPAW;HBEGFA;GPI1;AMELX;NUDT6
interleukin-7 receptor binding
protein bindingIL17RA;TRIM41;PFTK1;AGPAT1;RNF146;MTMR9;MAP1S;GABPB2;DHX36

Il7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il7 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il7.

IL7R; IL2RG

Research Area

Related articles

Bystrom, S; Ayoglu, B; et al. Affinity Proteomic Profiling of Plasma, Cerebrospinal Fluid, and Brain Tissue within Multiple Sclerosis. JOURNAL OF PROTEOME RESEARCH 13:4607-4619(2014).
Ramdasi, AY; Arya, RP; et al. Effect of Pregnancy on Anti-HEV Antibody Titres, Plasma Cytokines and the Corresponding Gene Expression Levels in the PBMCs of Patients Presenting with Self-Recovering Clinical and Subclinical Hepatitis E. PLOS ONE 9:-(2014).
  • Q&As
  • Reviews

Q&As (6)

Ask a question
What are the application scenarios of IL7? 10/10/2020

IL7 is widely used in the research and development of immunotherapy protocols, can enhance the body's immune function, for the treatment of cancer, infection, autoimmune diseases and other diseases.

What is the mechanism of IL7 in the treatment of bladder cancer? 11/25/2019

IL7 can activate the body's immune system and enhance the immune cells' attack on bladder cancer.

What is the optimal dose of IL7 in the treatment of leukemia? 07/18/2019

The dosage of IL7 in the treatment of leukemia needs to be calculated individually according to the specific situation of the patient.

Does the efficacy of IL7 in the treatment of infectious diseases? 04/10/2019

It can enhance the function of the body's immune system, and has a certain effect on some infectious diseases.

Are there have any efficacy of IL7 in the treatment of specific cancers? 03/31/2019

Recombinant IL7 protein may have some therapeutic effect on specific cancers by activating T cells, but further clinical studies are needed.

How to prepare IL7? 03/27/2019

This is obtained by recombinant DNA technology, inserting foreign genes into the host expression system, and then through purification and other steps.

Customer Reviews (3)

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Reviews
03/27/2022

    Effective in signal transduction pathway.

    04/17/2021

      IL7 has good absorbability and high bioavailability.

      11/27/2020

        Good stability under different environmental conditions

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