Recombinant Mouse Mstn Protein (Asn25-Ser265), C-His tagged

• Cat.No.: Mstn-5425M
• Product Overview: Recombinant mouse GDF8 (Asn25-Ser265) fused with the C-terminal His tag was expressed in mammalian cells.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: His
• Protein Length: Asn25-Ser265
• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Homozygous knockout mice for this gene exhibit increased muscle mass and bone density, and reduced adiposity.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 26.51 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Mstn myostatin [ Mus musculus (house mouse) ]
• Official Symbol: Mstn
• Synonyms: Mstn; myostatin; Cmpt; Gdf8; growth/differentiation factor 8
• Gene ID: 17700
• mRNA Refseq: NM_010834
• Protein Refseq: NP_034964
• UniProt ID: O08689