Recombinant Pig MSTN protein, His-tagged

• Cat.No.: MSTN-1754P
• Product Overview: Recombinant Pig MSTN aa. (Asp267~Ser375) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Pig
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 14kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Asp267~Ser375
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >98%
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; Reporter Assays; Purification; Amine Reactive Labeling.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200μg/mL
• Storage buffer: PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300.
• Reconstitution: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Isoelectric Point: 6.9

Gene Information

• Gene Name: MSTN myostatin [ Sus scrofa (pig) ]
• Official Symbol: MSTN
• Synonyms: MSTN; GDF8; GDF8:MSTN; growth/differentiation factor 8; GDF-8; growth differentiation factor 8
• Gene ID: 399534
• mRNA Refseq: NM_214435.2
• Protein Refseq: NP_999600.2
• UniProt ID: Q6SVB3

Reviews

04/04/2021

The MSTN protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.

11/15/2020

the manufacturer of MSTN provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.

02/01/2020

The outstanding level of customer service adds extra reassurance and confidence in using the MSTN protein for my scientific investigations.

Q&As

How do MSTN inhibitors work in the context of muscle-related disorders?

MSTN inhibitors work by blocking the activity of the MSTN protein, thus promoting muscle growth and potentially reversing muscle loss.

Are there any known side effects of using MSTN inhibitors in clinical trials?

Some potential side effects include joint stiffness, increased risk of fractures, and insulin resistance, which require close monitoring during trials.

How does the overexpression of MSTN affect muscle development?

Overexpression of MSTN can lead to muscle atrophy and decreased muscle mass.

How do researchers regulate the dosage of MSTN protein therapy to ensure safety and efficacy?

Researchers carefully monitor the dosage and administration of MSTN protein therapy through preclinical and clinical studies to establish the optimal therapeutic dose.

What are the potential risks associated with MSTN protein therapy?

Possible risks include unintended effects on other organ systems and potential complications related to excessive muscle growth.