Recombinant Mouse TNFSF11 Protein
Cat.No. : | TNFSF11-683M |
Product Overview : | Recombinant Mouse TNFSF11 Protein is produced by E.coli expression system. |
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Description : | TRANCE, also known as tumor necrosis factor ligand superfamily member 11, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. TRANCE also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. TRANCE is important in bone metabolism. This natural and necessary surface-bound molecule (also known as CD254) found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption. Recombinant Mouse TRANCE protein was expressed in E.coli and purified by using conventional chromatography. |
Source : | E. coli |
Species : | Mouse |
Form : | Liquid. In Tris-Hcl buffer(pH 8.5) containing 0.1 M NaCl. |
Molecular Mass : | 17.9 kDa |
Protein length : | 158-316 aa |
AA Sequence : | MKPEAQPFAH LTINAASIPS GSHKVTLSSW YHDRGWAKIS NMTLSNGKLR VNQDGFYYLY ANICFRHHET SGSVPTDYLQ LMVYVVKTSI KIPSSHNLMK GGSTKNWSGN SEFHFYSINV GGFFKLRAGE EISIQVSNPS LLDPDQDATY FGAFKVQDID |
Endotoxin : | < 1.0 EU per 1 ug of protein (determined by LAL method) |
Purity : | > 90 % by SDS - PAGE |
Notes : | For research use only. This product is not intended or approved for human, diagnostics or veterinary use. |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 [ Mus musculus ] |
Official Symbol : | TNFSF11 |
Synonyms : | Tumor necrosis factor ligand superfamily member 11; Ly109l; ODF; OPGL; |
Gene ID : | 21943 |
mRNA Refseq : | NM_011613 |
Protein Refseq : | NP_035743 |
UniProt ID : | O35235 |
Products Types
◆ Recombinant Protein | ||
TNFSF11-4498H | Recombinant Human TNFSF11 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF11-2025R | Recombinant Rat TNFSF11 Protein | +Inquiry |
TNFSF11-5859R | Recombinant Rat TNFSF11 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF11-2023M | Recombinant Mouse TNFSF11 Protein, His-tagged | +Inquiry |
TNFSF11-2022H | Recombinant Human TNFSF11 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
TNFSF11-998HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
TNFSF11-1093HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
TNFSF11-1586MCL | Recombinant Mouse TNFSF11 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIt is possible to detect the expression level of TNFSF11 protein to help diagnose tumors and other diseases, and to assess their prognosis and treatment effectiveness.
At present, a variety of drugs have been developed to target TNFSF11 proteins and their related signaling pathways, including inhibiting their expression and inhibiting their binding to receptors, etc., for the treatment of tumors and other bone metabolism-related diseases.
Studies have shown that TNFSF11 proteins can be involved in the regulation of infectious diseases, such as playing a role in some viral infections.
There are differences in the expression of TNFSF11 proteins in different tissues and organs, and they are expressed in tissues and organs such as the immune system, bones, and teeth, and the expression level may be affected by many factors.
Studies have shown that TNFSF11 proteins can be involved in the regulation of autoimmune diseases, such as in autoimmune diseases such as rheumatoid arthritis.
TNFSF11 protein belongs to the TNF superfamily and has certain structural and functional similarities with other members of the TNF superfamily.
Customer Reviews (3)
Write a reviewThe reproducibility of TNFSF11 is so good that the results are highly consistent regardless of the conditions under which the experiment or application is performed, greatly reducing the experimental error.
Green production process of TNFSF11 is highly commendable, which uses the most advanced biotechnology to increase production efficiency and reduce environmental impact.
The short half-life and high clearance of TNFSF11 make it better able to adapt to changing treatment needs and provide patients with more flexible treatment options.
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