Expand Expand| Cat.No. : | TNFSF11-683M |
| Product Overview : | Recombinant Mouse TNFSF11 Protein is produced by E.coli expression system. |
| Description : | TRANCE, also known as tumor necrosis factor ligand superfamily member 11, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. TRANCE also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. TRANCE is important in bone metabolism. This natural and necessary surface-bound molecule (also known as CD254) found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption. Recombinant Mouse TRANCE protein was expressed in E.coli and purified by using conventional chromatography. |
| Source : | E. coli |
| Species : | Mouse |
| Form : | Liquid. In Tris-Hcl buffer(pH 8.5) containing 0.1 M NaCl. |
| Molecular Mass : | 17.9 kDa |
| Protein length : | 158-316 aa |
| AA Sequence : | MKPEAQPFAH LTINAASIPS GSHKVTLSSW YHDRGWAKIS NMTLSNGKLR VNQDGFYYLY ANICFRHHET SGSVPTDYLQ LMVYVVKTSI KIPSSHNLMK GGSTKNWSGN SEFHFYSINV GGFFKLRAGE EISIQVSNPS LLDPDQDATY FGAFKVQDID |
| Endotoxin : | < 1.0 EU per 1 ug of protein (determined by LAL method) |
| Purity : | > 90 % by SDS - PAGE |
| Notes : | For research use only. This product is not intended or approved for human, diagnostics or veterinary use. |
| Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 or -70 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : | 1 mg/ml (determined by Bradford assay) |
| Figure : |
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| Gene Name : | Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 [ Mus musculus ] |
| Official Symbol : | TNFSF11 |
| Synonyms : | Tumor necrosis factor ligand superfamily member 11; Ly109l; ODF; OPGL; |
| Gene ID : | 21943 |
| mRNA Refseq : | NM_011613 |
| Protein Refseq : | NP_035743 |
| UniProt ID : | O35235 |
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