Recombinant Human TNFSF11 protein, His-Flag-tagged

• Cat.No.: TNFSF11-762H
• Product Overview: Human RANKL Trimer Protein is expressed from mammalian with His Tag and Flag Tag at the N-terminal. It contains Leu160-Val313 trimer design.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: Leu160-Val313
• Description: RANK L (receptor activator of NF-kappa B ligand), also called TRANCE (TNF-related activation-induced cytokines), OPGL (osteoprotegerin ligand), or ODF (osteoclast differentiation factor), is a 39‑45 kDa type II transmembrane (TM) protein in the tumor necrosis factor family, designated TNFSF11.RANK L is cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 55.2KDa.
• Endotoxin: Less than 1EU per ug by the LAL method.
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: TNFSF11 TNF superfamily member 11 [ Homo sapiens (human) ]
• Official Symbol: TNFSF11
• Synonyms: CD254 antigen; CD254; ODF; OPGL; OPGLOPTB2; Osteoclast differentiation factor; Osteoprotegerin ligand; RANK L; RANKL; RANKLreceptor activator of nuclear factor kappa B ligand; Receptor activator of nuclear factor kappa-B ligand; sOdf; TNF-related activation-induced cytokine; TNFSF11; TRANCE; TRANCEODFhRANKL2; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11
• Gene ID: 8600
• mRNA Refseq: NM_003701.4
• Protein Refseq: NP_003692.1
• MIM: 602642
• UniProt ID: O14788