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Recombinant Mouse/Rat FGF1 Protein

Cat.No. : FGF1-79M
Product Overview : Recombinant Mouse/Rat FGF1 Protein without tag was expressed in E. coli.
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Description : Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of FGF-acidic are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of FGF-acidic during T2DM.
Source : E. coli
Species : Mouse/Rat
Bio-activity : No biological activity data is available at this time.
Molecular Mass : Monomer, 15.9 kDa (141 aa)
AA Sequence : MFNLPLGNYKKPKLLYCSNGGHFLR ILPDGTVDGTRDRSDQHIQLQLSAE SAGEVYIKGTETGQYLAMDTEGLLY GSQTPNEECLFLERLEENHYNTYTS KKHAEKNWFVGLKKNGSCKRGPRTH YGQKAILFLPLPVSSD
Endotoxin : ≤1 EUs/μg, Kinetic LAL
Purity : ≥95%, Reducing and Non-Reducing SDS PAGE
Stability : 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
1 month when stored at 4 centigrade after reconstituting as directed.
3 months when stored at -20 to -80 centigrade after reconstituting as directed.
Storage : Storage Prior to Reconstitution: -20 centigrade
Storage Buffer : Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 75 mM sodium chloride, pH 7.5
Reconstitution : Sterile water at 0.1 mg/mL
Shipping : Room temperature
Instructions : Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.
Gene Name : Fgf1 fibroblast growth factor 1 [ Mus musculus (house mouse) ]
Official Symbol : FGF1
Synonyms : FGF1; fibroblast growth factor 1; aFGF; HBGF-1; acidic fibroblast growth factor; heparin-binding growth factor 1; fibroblast growth factor 1 (acidic); Fam; Fgfa; Dffrx; Fgf-1;
Gene ID : 14164
mRNA Refseq : NM_010197
Protein Refseq : NP_034327
UniProt ID : P61148

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any clinical trials using FGF1 for heart disease? 06/28/2020

Yes, there have been clinical trials exploring the use of FGF1 in treating heart disease, specifically in promoting cardiac angiogenesis.

Can FGF1 be used in regenerative medicine? 09/15/2018

Yes, FGF1 is being investigated for its potential in regenerative medicine to repair damaged tissues and organs.

Can FGF1 be used in the treatment of diabetes? 03/29/2018

FGF1 has shown potential in improving insulin sensitivity and glucose regulation in preclinical studies, but further research is needed for clinical applications.

What safety concerns are associated with FGF1 use? 01/15/2017

Safety concerns include the risk of uncontrolled cell growth, which could lead to cancer, and the need for precise dosing and administration.

Are there any side effects associated with FGF1 therapy? 12/10/2016

Potential side effects may include inflammation at the application site, allergic reactions, and adverse effects related to uncontrolled cell growth.

Customer Reviews (3)

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Reviews
08/06/2021

    By using FGF1 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.

    06/03/2021

      The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.

      11/25/2018

        As a researcher utilizing FGF1 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.

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