Recombinant Mouse/Rat FGF1 Protein
Cat.No. : | FGF1-79M |
Product Overview : | Recombinant Mouse/Rat FGF1 Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of FGF-acidic are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of FGF-acidic during T2DM. |
Source : | E. coli |
Species : | Mouse/Rat |
Bio-activity : | No biological activity data is available at this time. |
Molecular Mass : | Monomer, 15.9 kDa (141 aa) |
AA Sequence : | MFNLPLGNYKKPKLLYCSNGGHFLR ILPDGTVDGTRDRSDQHIQLQLSAE SAGEVYIKGTETGQYLAMDTEGLLY GSQTPNEECLFLERLEENHYNTYTS KKHAEKNWFVGLKKNGSCKRGPRTH YGQKAILFLPLPVSSD |
Endotoxin : | ≤1 EUs/μg, Kinetic LAL |
Purity : | ≥95%, Reducing and Non-Reducing SDS PAGE |
Stability : | 12 months from date of receipt when stored at -20 to -80 centigrade as supplied. 1 month when stored at 4 centigrade after reconstituting as directed. 3 months when stored at -20 to -80 centigrade after reconstituting as directed. |
Storage : | Storage Prior to Reconstitution: -20 centigrade |
Storage Buffer : | Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 75 mM sodium chloride, pH 7.5 |
Reconstitution : | Sterile water at 0.1 mg/mL |
Shipping : | Room temperature |
Instructions : | Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws. |
Gene Name : | Fgf1 fibroblast growth factor 1 [ Mus musculus (house mouse) ] |
Official Symbol : | FGF1 |
Synonyms : | FGF1; fibroblast growth factor 1; aFGF; HBGF-1; acidic fibroblast growth factor; heparin-binding growth factor 1; fibroblast growth factor 1 (acidic); Fam; Fgfa; Dffrx; Fgf-1; |
Gene ID : | 14164 |
mRNA Refseq : | NM_010197 |
Protein Refseq : | NP_034327 |
UniProt ID : | P61148 |
Products Types
◆ Native Protein | ||
FGF1-26203TH | Native Human FGF1 | +Inquiry |
FGF1-33B | Active Native Bovine FGF1 | +Inquiry |
◆ Lysates | ||
FGF1-6252HCL | Recombinant Human FGF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there have been clinical trials exploring the use of FGF1 in treating heart disease, specifically in promoting cardiac angiogenesis.
Yes, FGF1 is being investigated for its potential in regenerative medicine to repair damaged tissues and organs.
FGF1 has shown potential in improving insulin sensitivity and glucose regulation in preclinical studies, but further research is needed for clinical applications.
Safety concerns include the risk of uncontrolled cell growth, which could lead to cancer, and the need for precise dosing and administration.
Potential side effects may include inflammation at the application site, allergic reactions, and adverse effects related to uncontrolled cell growth.
Customer Reviews (3)
Write a reviewBy using FGF1 protein, I can explore the mechanisms underlying cell division, cell cycle control, and the molecular pathways associated with these processes.
The protein's interaction with other APC/C subunits enables the study of its function and the investigation of its involvement in various cellular processes.
As a researcher utilizing FGF1 protein in my trials, I can highlight its advantages and the valuable support provided by the manufacturer in facilitating my research.
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