Recombinant Rat Il1rn, His-tagged

• Cat.No.: Il1rn-107R
• Product Overview: Recombinant rat Il1rn, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Il1rn also known as Interleukin-1 receptor antagonist protein is a member of the interleukin 1 cytokine family. Il1rn may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is no limit the pro-inflammatory signals but most prominently by mononuclear phagocytes and keratinocytes. Il1rn is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.
• Source: E.coli
• Species: Rat
• Tag: His
• Form: Liquid. In Phosphate Buffer Saline (pH7.4) containing 10% glycerol, 1mM DTT
• Molecular Mass: 19.8kDa (175aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHPAGKRP CKMQAFRIWD TNQKTFYLRN NQLIAGYLQG PNTKLEEKID MVPIDFRNVF LGIHGGKLCL SCVKSGDDTK LQLEEVNITD LNKNKEEDKR FTFIRSETGP TTSFESLACP GWFLCTTLEA DHPVSLTNTP KEPCTVTKFY FQEDQ
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Il1rn interleukin 1 receptor antagonist [ Rattus norvegicus ]
• Official Symbol: Il1rn
• Synonyms: IL1RN; interleukin 1 receptor antagonist; interleukin-1 receptor antagonist protein; IRAP; IL-1RN; IL1 inhibitor; IL-1ra
• Gene ID: 60582
• mRNA Refseq: NM_022194
• Protein Refseq: NP_071530
• Pathway: IL-1 Signaling Pathway, organism-specific biosystem
• Function: interleukin-1 Type I receptor antagonist activity; interleukin-1 Type II receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor binding; interleukin-1, Type I receptor binding; interleukin-1, Type I receptor binding; interleukin-1, Type II receptor binding