| Description : |
This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. |
| Source : |
HEK293 |
| Species : |
Rhesus macaque |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
44.6 kDa |
| Protein Length : |
855 |
| AA Sequence : |
MILIPRMLLVLFLLLPILSSAKAQV NPAICRYPLGMSGGQIPDEDITASS QWSESTAAKYGRLDSEEGDGAWCPE IPVEPDDLKEFLQIDLHTLHFITLV GTQGRHAGGHGIEFAPMYKINYSRD GTRWISWRNRHGKQVLDGNSNPYDI FLKDLEPPIVARFVRFIPVTDHSMN VCMRVELYGCVWLDGLVSYNAPAGQ QFVLPGGSIIYLNDSVYDGAVGYSM TEGLGQLTDGVSGLDDFTQTHEYHV WPGYDYVGWRNESATNGYIEIMFEF DRIRNFTTMKVHCNNMFAKGVKIFK EVQCYFRSEASEWEPNAISFPLVLD DVNPSARFVTVPLHHRMASAIKCQY HFADTWMMFSEITFQSDAAMYNNSG ALPTSPMTPTTYDPMLKIDDSNTRI LIGCLVAIIFILLAIIVIILWRQFW QKMLEKASRRMLDDEMTVSLSLPSD SSMFNNNRSSSPSEQESNSTYDRIF PLRPDYQEPSRLIRKLPEFAPGEEE SGCSGVVKPVQPSGPEGVPHYAEAD IVNLQGVTGGNTYSVPAVTMDLLSG KDVAVEEFPRKLLTFKEKLGEGQFG EVHLCEVEGMEKFKDKDFALDVSAN QPVLVAVKMLRADANKNARNDFLKE IKIMSRLKDPNIIHLLAVCITDDPL CMITEYMENGDLNQFLSRHEPPNSS SSNVPTVSYTNLKFMATQIASGMKY LSSLNFVHRDLATRNCLVGKNYTIK IADFGMSRNLYSGDYYRIQGRAVLP IRWMSWESILLGKFTTASDVWAFGV TLWETFTFCQEQPYSQLSDEQVIEN TGEFFRDQGRQTYLPQPAICPDSVY KLMLSCWRRDTKNRPSFQEIHLLLL QQGDE |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
