• Official Full Name
  • adaptor-related protein complex 3, beta 1 subunit
  • Background
  • This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
  • Synonyms
  • AP3B1; adaptor-related protein complex 3, beta 1 subunit; PE; HPS; HPS2; ADTB3; ADTB3A; AP-3 complex subunit beta-1; beta-3A-adaptin; AP-3 complex beta-3A subunit; adaptor protein complex AP-3 subunit beta-1; clathrin assembly protein complex 3 beta-1 large chain;
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human AP3B1, His-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AP3B1 protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AP3B1, GST-tagged
Source (Host):Species:Human
Product nameRecombinant Human AP3B1 293 Cell Lysate

Involved Pathway

AP3B1 involved in several pathways and played different roles in them. We selected most pathways AP3B1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP3B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein

Protein Function

AP3B1 has several biochemical functions, for example, GTP-dependent protein binding, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP3B1 itself. We selected most functions AP3B1 had, and list some proteins which have the same functions with AP3B1. You can find most of the proteins on our site.
Related Protein
Function GTP-dependent protein binding
Related Protein RAPGEF5; CDC42; RAPGEF6; AP1G1; GCH1; AP3B1; RAB32; GCHFR; MRAS; PARD6A
Function protein phosphatase binding
Related Protein CDH2; GNB2L1; VCP; HSP90B1; TRAF3; LCK; EIF2AK3; RPA3; VCAN; FGF19

Interacting Protein

AP3B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP3B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP3B1.
ARRB2; ARRB1; pmbA; pi3p; 15-deoxy-delta(12,14; Lyplal1; PTBP3; YWHAZ; SNW1; LRRK2; SKA3; DLG3; NLRP3; Nup155; EPB41L3