|Official Full Name||arylsulfatase A|
|Background||The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010]|
|Synonyms||ARSA; arylsulfatase A; MLD; ASA; cerebroside-sulfatase;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ARSA involved in several pathways and played different roles in them. We selected most pathways ARSA participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARSA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Sphingolipid metabolism||PPAP2C; NEU3.3; PPAP2A; CERS1; SPTLC2A; LASS5; ARSE; SGPP1; ARSJ; ASAH1B|
|Lysosome||CTSH; AP1M1; AP3D1; GLA; GUSB; GGA2; CTSF; CD164; AGA; LAPTM5|
ARSA has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by ARSA itself. We selected most functions ARSA had, and list some proteins which have the same functions with ARSA. You can find most of the proteins on our site.
|arylsulfatase activity||ARSF; SULF2; SULF1; ARSB; ARSH; ARSK; ARSD; ARSJ; ARSE; ARSG|
|calcium ion binding||SLC25A25B; CRB2B; CABYR; PCDH1G18; PCDHGA10; PCDH1A4; CALUA; FKBP9; SULF2B; PLCD1|
|protein binding||RAB9B; ADAM1B; METTL17; PPM1K; DOK4; CARD10; BIN1; HELLS; COL6A2; AIP|
|sulfuric ester hydrolase activity||GNS; SGSH; GNSB; SULF2B; GALNS; GNSA; ARSA; STS; SULF2A|
ARSA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARSA here. Most of them are supplied by our site. Hope this information will be useful for your research of ARSA.
TRIP13; TFAP2A; CETN2; PPIC; CLEC4G; xylB