ARSA

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ARSA

Official Full Name arylsulfatase A
Background The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010]
Synonyms ARSA; arylsulfatase A; MLD; ASA; cerebroside-sulfatase;
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARSA-2324H Recombinant Human ARSA, His tagged Human Cell His
    Human ARSA-26265TH Recombinant Human ARSA Wheat Germ N/A
    Human ARSA-2826H Recombinant Human ARSA Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ARSA-306H Recombinant Human ARSA, His-tagged NS0 His
    Human ARSA-3086HCL Recombinant Human ARSA cell lysate Human Cell N/A
    Human ARSA-533H Recombinant Human ARSA Protein, His-tagged E.coli His
    Human ARSA-572H Recombinant Human arylsulfatase A, His-tagged E.coli His
    Human ARSA-861H Recombinant Human ARSA protein, GST-tagged Wheat Germ GST
    Human ARSA-9897H Recombinant Human ARSA, GST-tagged E.coli GST
    Mouse Arsa-2334M Recombinant Mouse Arsa, His tagged Human Cell His
    Mouse ARSA-3085MCL Recombinant Mouse ARSA cell lysate Human Cell N/A
    Zebrafish ARSA-2206Z Recombinant Zebrafish ARSA Mammalian Cell His

    ARSA involved in several pathways and played different roles in them. We selected most pathways ARSA participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARSA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Sphingolipid metabolism PPAP2C; NEU3.3; PPAP2A; CERS1; SPTLC2A; LASS5; ARSE; SGPP1; ARSJ; ASAH1B
    Lysosome CTSH; AP1M1; AP3D1; GLA; GUSB; GGA2; CTSF; CD164; AGA; LAPTM5

    ARSA has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by ARSA itself. We selected most functions ARSA had, and list some proteins which have the same functions with ARSA. You can find most of the proteins on our site.

    Function Related Protein
    arylsulfatase activity ARSF; SULF2; SULF1; ARSB; ARSH; ARSK; ARSD; ARSJ; ARSE; ARSG
    calcium ion binding SLC25A25B; CRB2B; CABYR; PCDH1G18; PCDHGA10; PCDH1A4; CALUA; FKBP9; SULF2B; PLCD1
    cerebroside-sulfatase activity ARSA
    protein binding RAB9B; ADAM1B; METTL17; PPM1K; DOK4; CARD10; BIN1; HELLS; COL6A2; AIP
    sulfuric ester hydrolase activity GNS; SGSH; GNSB; SULF2B; GALNS; GNSA; ARSA; STS; SULF2A

    ARSA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARSA here. Most of them are supplied by our site. Hope this information will be useful for your research of ARSA.

    TRIP13; TFAP2A; CETN2; PPIC; CLEC4G; xylB

    Mitsunaga-Nakatsubo, K; Kusunoki, S; et al. Cell-surface arylsulfatase A and B on sinusoidal endothelial cells, hepatocytes, and Kupffer cells in mammalian livers. MEDICAL MOLECULAR MORPHOLOGY 42:63-69(2009).
    Kurdi-Haidar, B; Heath, D; et al. Immunohistochemical analysis of the distribution of the human ATPase (hASNA-I) in normal tissues and its overexpression in breast adenomas and carcinomas. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 46:1243-1248(1998).

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