arsa
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  • Official Full Name
  • arylsulfatase A
  • Background
  • The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • Synonyms
  • ARSA; arylsulfatase A; MLD; ASA; cerebroside-sulfatase;
Cat.#:ARSA-2826HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARSA Protein, MYC/DDK-tagged
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Cat.#:ARSA-533HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARSA Protein, His-tagged
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Cat.#:ARSA-2324HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARSA, His tagged
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Cat.#:ARSA-26265THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ARSA
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Cat.#:ARSA-306HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human ARSA, His-tagged
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Cat.#:ARSA-572HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human arylsulfatase A, His-tagged
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Cat.#:ARSA-861HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ARSA protein, GST-tagged
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Cat.#:ARSA-9897HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARSA, GST-tagged
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Cat.#:Arsa-2334MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Arsa, His tagged
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Cat.#:ARSA-2206ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ARSA
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Cat.#:ARSA-3086HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ARSA cell lysate
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Cat.#:ARSA-3085MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse ARSA cell lysate
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Involved Pathway

Arsa involved in several pathways and played different roles in them. We selected most pathways Arsa participated on our site, such as Sphingolipid metabolism, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with Arsa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Sphingolipid metabolism
UGT8A; GBA; ARSH; PPAP2A; SMPD1; ARSK; GAL3ST1; SPTLC2; ARSI; SPTLC2B
Lysosome
GALCB; GNSB; AP1M3; ACP2; PPT1; CTNS; CTSF; ACP5A; ATP6V0A2; AP1G2

Protein Function

Arsa has several biochemical functions, for example, arylsulfatase activity, calcium ion binding, cerebroside-sulfatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Arsa itself. We selected most functions Arsa had, and list some proteins which have the same functions with Arsa. You can find most of the proteins on our site.
Function
Related Protein
Function arylsulfatase activity
Related Protein SULF2; ARSI; ARSG; ARSA; ARSD; ARSB; ARSF; SULF1; ARSE; ARSJ
Function calcium ion binding
Related Protein FBLN7; S100A10; TPO; PCDH2G9; MATN3A; CAPN2; JAG2; FKBP14; MMP24; CELSR3
Function cerebroside-sulfatase activity
Related Protein ARSA
Function protein binding
Related Protein SYT2; UQCRH; ACVR2B; C16orf48; LIMA1; FERMT2; CHRD; CDK17; HRAS; KHDC1A
Function sulfuric ester hydrolase activity
Related Protein SGSH; SULF2B; GNS; GNSB; GALNS; STS; GNSA; ARSA; SULF2A

Interacting Protein

Arsa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Arsa here. Most of them are supplied by our site. Hope this information will be useful for your research of Arsa.
TRIP13; TFAP2A; CETN2; PPIC; CLEC4G; xylB

Arsa Related Articles

Mitsunaga-Nakatsubo, K; Kusunoki, S; et al. Cell-surface arylsulfatase A and B on sinusoidal endothelial cells, hepatocytes, and Kupffer cells in mammalian livers. MEDICAL MOLECULAR MORPHOLOGY 42:63-69(2009).
Kurdi-Haidar, B; Heath, D; et al. Immunohistochemical analysis of the distribution of the human ATPase (hASNA-I) in normal tissues and its overexpression in breast adenomas and carcinomas. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 46:1243-1248(1998).