Recombinant Human arylsulfatase A, His-tagged
Cat.No. : | ARSA-572H |
Product Overview : | ARSA, 21-509aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | ARSA hydrolyzes cerebrosidesulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. Recombinant human ARSA protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol |
Molecular Mass : | 54.3kDa (512aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSRPPNIVL IFADDLGYGD LGCYGHPSST TPNLDQLAAG GLRFTDFYVP VSLCTPSRAA LLTGRLPVRM GMYPGVLVPS SRGGLPLEEV TVAEVLAARG YLTGMAGKWH LGVGPEGAFL PPHQGFHRFL GIPYSHDQGP CQNLTCFPPA TPCDGGCDQG LVPIPLLANL SVEAQPPWLP GLEARYMAFA HDLMADAQRQ DRPFFLYYAS HHTHYPQFSG QSFAERSGRG PFGDSLMELD AAVGTLMTAI GDLGLLEETL VIFTADNGPE TMRMSRGGCS GLLRCGKGTT YEGGVREPAL AFWPGHIAPG VTHELASSLD LLPTLAALAG APLPNVTLDG FDLSPLLLGT GKSPRQSLFF YPSYPDEVRG VFAVRTGKYK AHFFTQGSAH SDTTADPACH ASSSLTAHEP PLLYDLSKDP GENYNLLGGV AGATPEVLQA LKQLQLLKAQ LDAAVTFGPS QVARGEDPAL QICCHPGCTP RPACCHCPDP HA |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | ARSA arylsulfatase A [ Homo sapiens ] |
Official Symbol : | ARSA |
Synonyms : | ARSA; arylsulfatase A; metachromatic leucodystrophy; ASA; cerebroside-sulfatase; MLD; |
Gene ID : | 410 |
mRNA Refseq : | NM_000487 |
Protein Refseq : | NP_000478 |
MIM : | 607574 |
UniProt ID : | P15289 |
Chromosome Location : | 22q13.31-qter |
Pathway : | Glycosphingolipid metabolism, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem; |
Function : | arylsulfatase activity; calcium ion binding; cerebroside-sulfatase activity; hydrolase activity; sulfuric ester hydrolase activity; |
Products Types
◆ Recombinant Protein | ||
ARSA-14H | Active Recombinant Human ARSA Protein (21-509), C-His-tagged | +Inquiry |
ARSA-533H | Recombinant Human ARSA Protein, His-tagged | +Inquiry |
ARSA-2826H | Recombinant Human ARSA Protein, MYC/DDK-tagged | +Inquiry |
Arsa-654M | Recombinant Mouse Arsa Protein, MYC/DDK-tagged | +Inquiry |
ARSA-2502H | Recombinant Human ARSA Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ARSA-3085MCL | Recombinant Mouse ARSA cell lysate | +Inquiry |
ARSA-3086HCL | Recombinant Human ARSA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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