| Description : |
The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. |
| Source : |
Sf9 cells |
| Species : |
Human |
| Tag : |
C-His |
| Bio-activity : |
Specific activity is > 2,500 pmol/min/μg, and defined as the amount of enzyme that hydrolyze 4-Nitrocatechol at pH 5.0 at 37 centigrade. |
| Molecular Mass : |
53.0 kDa |
| Protein Length : |
21-509 |
| AA Sequence : |
ADPRPPNIVLIFADDLGYGDLGCYG HPSSTTPNLDQLAAGGLRFTDFYVP VSLCTPSRAALLTGRLPVRMGMYPG VLVPSSRGGLPLEEVTVAEVLAARG YLTGMAGKWHLGVGPEGAFLPPHQG FHRFLGIPYSHDQGPCQNLTCFPPA TPCDGGCDQGLVPIPLLANLSVEAQ PPWLPGLEARYMAFAHDLMADAQRQ DRPFFLYYASHHTHYPQFSGQSFAE RSGRGPFGDSLMELDAAVGTLMTAI GDLGLLEETLVIFTADNGPETMRMS RGGCSGLLRCGKGTTYEGGVREPAL AFWPGHIAPGVTHELASSLDLLPTL AALAGAPLPNVTLDGFDLSPLLLGT GKSPRQSLFFYPSYPDEVRGVFAVR TGKYKAHFFTQGSAHSDTTADPACH ASSSLTAHEPPLLYDLSKDPGENYN LLGGVAGATPEVLQALKQLQLLKAQ LDAAVTFGPSQVARGEDPALQICCH PGCTPRPACCHCPDPHAHHHHHH. |
| Purity : |
Greater than 95.0% as determined by SDS-PAGE. |
| Notes : |
Our products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
| Storage : |
Store at 4 centigrade if entire vial will be used within 2-4 weeks. Store, frozen at -20 centigrade for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Concentration : |
0.25 mg/mL |
| Storage Buffer : |
Phosphate Buffered Saline (pH 7.4) and 10% glycerol. |
