angptl3
Share
  • Official Full Name
  • angiopoietin-like 3
  • Background
  • This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Feb 2013]
  • Synonyms
  • ANGPTL3; angiopoietin-like 3; ANL3; ANG-5; FHBL2; ANGPT5; angiopoietin-related protein 3; angiopoietin 5;
Cat.#:ANGPTL3-117HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANGPTL3 Protein, His-tagged
+Inquiry
Cat.#:ANGPTL3-432HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human ANGPTL3 Protein (Met1-Glu460), His-tagged
+Inquiry
Cat.#:ANGPTL3-783MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse ANGPTL3 Protein (Met1-Thr455), His-tagged
+Inquiry
Cat.#:ANGPTL3-176HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANGPTL3, His-tagged
+Inquiry
Cat.#:ANGPTL3-32HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANGPTL3 protein, His-tagged
+Inquiry
Cat.#:ANGPTL3-397HTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANGPTL3, FLAG-tagged
+Inquiry
Cat.#:ANGPTL3-487HTag:His
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human ANGPTL3 Protein, His-tagged
+Inquiry
Cat.#:ANGPTL3-555HTag:His
Source (Host):HamsterSpecies:Human
Product nameRecombinant Human ANGPTL3 protein, His-tagged
+Inquiry
Cat.#:ANGPTL3-556HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANGPTL3 protein, GST-tagged
+Inquiry
Cat.#:ANGPTL3-9649HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANGPTL3, GST-tagged
+Inquiry
Cat.#:Angptl3-173MTag:His
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Angptl3 Protein, His-tagged, Biotinylated
+Inquiry
Cat.#:Angptl3-1819MTag:His|GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Angptl3 protein, His & GST-tagged
+Inquiry
Cat.#:Angptl3-1820MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Angptl3 protein, His & T7-tagged
+Inquiry
Cat.#:ANGPTL3-3866CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ANGPTL3
+Inquiry
Cat.#:ANGPTL3-9329ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ANGPTL3
+Inquiry
Cat.#:ANGPTL3-399HTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANGPTL3, Fibrinogen-like Domain, FLAG-tagged
+Inquiry
Cat.#:ANGPTL3-400HTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human Angiopoietin-like 3, FLAG-tagged
+Inquiry
Cat.#:ANGPTL3-398MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse ANGPTL3, Coiled-Coil Domain, His-tagged
+Inquiry
Cat.#:ANGPTL3-401MTag:Flag
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Angiopoietin-like 3, FLAG-tagged
+Inquiry
Cat.#:ANGPTL3-101HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANGPTL3, His-tagged
+Inquiry
Cat.#:ANGPTL3-8862HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ANGPTL3 293 Cell Lysate
+Inquiry

Involved Pathway

ANGPTL3 involved in several pathways and played different roles in them. We selected most pathways ANGPTL3 participated on our site, such as Integrins in angiogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANGPTL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Integrins in angiogenesis
CSF1; MFGE8; EDIL3; ANGPTL3; CSF1R

Protein Function

ANGPTL3 has several biochemical functions, for example, enzyme inhibitor activity, growth factor activity, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANGPTL3 itself. We selected most functions ANGPTL3 had, and list some proteins which have the same functions with ANGPTL3. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme inhibitor activity
Related Protein DGKZ; CSN2; WFIKKN1; ANGPTL3; PDE6H; GCHFR; PPP1R12A; UGT1A1; KIAA1967; HSPBP1
Function growth factor activity
Related Protein CSF3; BDNF; CSF2; IL3; IL34; HDGF; MDKA; IL8L2; FGF6A; GDF6B
Function integrin binding
Related Protein THY1; ITGB5; SYK; ITGA3; COL16A1; ADAM2; CTGFB; FERMT3; ACTN3; S1PR2
Function phospholipase inhibitor activity
Related Protein ANXA3A; ANXA1C; ANXA2A; ANXA1A; ANXA5; ANXA4; APOC1; ANGPTL3; SNCB; ANXA2B

Interacting Protein

ANGPTL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANGPTL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANGPTL3.
ITGAV

ANGPTL3 Related Articles

Nakajima, K; Kobayashi, J; et al. Antibodies to human angiopoietin-like protein 3: a patent evaluation of WO2012174178. EXPERT OPINION ON THERAPEUTIC PATENTS 24:113-119(2014).
Chou, S; Lodish, HF; et al. Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107:7799-7804(2010).