Recombinant Full Length Human ANGPTL3 Protein, C-Flag-tagged

• Cat.No.: ANGPTL3-1785HFL
• Product Overview: Recombinant Full Length Human ANGPTL3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 51.4 kDa
• AA Sequence: MFTIKLLLFIVPLVISSRIDQDNSS FDSLSPEPKSRFAMLDDVKILANGL LQLGHGLKDFVHKTKGQIND IFQKLNIFDQSFYDLSLQTSEIKEE EKELRRTTYKLQVKNEEVKNMSLEL NSKLESLLEEKILLQQKVKY LEEQLTNLIQNQPETPEHPEVTSLK TFVEKQDNSIKDLLQTVEDQYKQLN QQHSQIKEIENQLRRTSIQE PTEISLSSKPRAPRTTPFLQLNEIR NVKHDGIPAECTTIYNRGEHTSGMY AIRPSNSQVFHVYCDVISGS PWTLIQHRIDGSQNFNETWENYKYG FGRLDGEFWLGLEKIYSIVKQSNYV LRIELEDWKDNKHYIEYSFY LGNHETNYTLHLVAITGNVPNAIPE NKDLVFSTWDHKAKGHFNCPEGYSG GWWWHDECGENNLNGKYNKP RAKSKPERRRGLSWKSQNGRLYSIK STKMLIHPTDSESFE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: ANGPTL3 angiopoietin like 3 [ Homo sapiens (human) ]
• Official Symbol: ANGPTL3
• Synonyms: ANL3; ANG-5; FHBL2; ANGPT5
• Gene ID: 27329
• mRNA Refseq: NM_014495.4
• Protein Refseq: NP_055310.1
• MIM: 604774
• UniProt ID: Q9Y5C1