Arhgdib

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Arhgdib

Official Full Name Rho GDP dissociation inhibitor (GDI) beta
Background Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM;179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization,;and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly;regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine;nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the;rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 (PubMed 8356058)).
Synonyms ARHGDIB; Rho GDP dissociation inhibitor (GDI) beta; GDIA2, GDID4, RAP1GN1; rho GDP-dissociation inhibitor 2; Ly GDI; RhoGDI2; Rho GDI 2; rho-GDI beta; D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARHGDIB-3480H Recombinant Human ARHGDIB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Arhgdib-646M Recombinant Mouse Arhgdib Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human ARHGDIB-1193H Recombinant Human ARHGDIB protein, His & GST-tagged E.coli His/GST
    Human ARHGDIB-1277H Recombinant Human Rho GDP Dissociation Inhibitor (GDI) Beta E.coli N/A
    Human ARHGDIB-21H Recombinant Human ARHGDIB protein, His-tagged E.coli His
    Human ARHGDIB-27088TH Recombinant Human ARHGDIB, GST-tagged E.coli GST
    Human ARHGDIB-29H Recombinant Human ARHGDIB, GST-tagged E.coli GST
    Human ARHGDIB-775H Recombinant Human ARHGDIB protein, GST-tagged Wheat Germ GST
    Human ARHGDIB-8735HCL Recombinant Human ARHGDIB 293 Cell Lysate HEK293 N/A
    Human ARHGDIB-9829H Recombinant Human ARHGDIB, GST-tagged E.coli GST
    Mouse ARHGDIB-1884M Recombinant Mouse ARHGDIB Protein Mammalian Cell His
    Chicken ARHGDIB-4780C Recombinant Chicken ARHGDIB Mammalian Cell His

    Arhgdib involved in several pathways and played different roles in them. We selected most pathways Arhgdib participated on our site, such as Neurotrophin signaling pathway, Vasopressin-regulated water reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Arhgdib were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neurotrophin signaling pathway NTRK1; MAPK9; MAPK10; NGF; MATK; TRP53; RPS6KA2; RELA; MAPK8; ABL1
    Vasopressin-regulated water reabsorption DCTN4; PRKACA; DYNC2H1; ARHGDIG; DCTN6; DCTN5; DYNC1LI1; CREB3L3; DYNC2LI1; AQP2

    Arhgdib has several biochemical functions, for example, GTPase activator activity, GTPase activity, Rho GDP-dissociation inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Arhgdib itself. We selected most functions Arhgdib had, and list some proteins which have the same functions with Arhgdib. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity STXBP5A; BAI3; ARHGDIG; SMAP2; NIPAL1; ABR; USP6NL; TBC1D9; ARHGEF6; TBC1D3
    GTPase activity RALAA; ATL1; HBS1L; RAB3AA; DNM2B; RASEF; NKIRAS1; RHOB; TUBA1A; RAB27B
    Rho GDP-dissociation inhibitor activity ARHGDIG; ARHGDIB; ARHGDIA

    Arhgdib has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Arhgdib here. Most of them are supplied by our site. Hope this information will be useful for your research of Arhgdib.

    RAC2; RAC3; UFM1; RAC1; ANKRD1; dacD; pepP; nagA; asd; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

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