Asah2
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Official Full Name
N-acylsphingosine amidohydrolase 2
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- CHO
- E.coli
- HEK293
- HEK293F
- HEK293T
- Human Cell
- Mammalian Cell
- His
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- N/A
- N
- C
- hFc
- Involved Pathway
- Protein Function
- Interacting Protein
- Asah2 Related Research Area
Asah2 involved in several pathways and played different roles in them. We selected most pathways Asah2 participated on our site, such as Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Asah2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid metabolism | LASS5;SMPD2;ARSJ;LASS4;FA2H;GLTPA;SGMS1;ASAH1;SPTLC2 |
| Metabolic pathways | MTMR2;GPIA;PLCD1A;G6PD;BDH1;CYP2C39;PTGDSB;ACY1;BCAT1 |
| Sphingolipid signaling pathway | MAPK1;PPP2R2B;LASS4;CERS5;SGMS2;RELA;AKT2;BID;SMPD2 |
Asah2 has several biochemical functions, for example, ceramidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Asah2 itself. We selected most functions Asah2 had, and list some proteins which have the same functions with Asah2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ceramidase activity | ASAH1B;ASAH1;ACER1;ASAH2 |
Asah2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Asah2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Asah2.
- Q&As
- Reviews
Q&As (7)
Ask a questionPost-translational modifications, such as phosphorylation, may impact ASAH2 activity, although further research is needed for a comprehensive understanding.
While specific inhibitors for ASAH2 are not yet available, researchers are actively exploring potential compounds that can modulate its activity.
ASAH2 is primarily localized in the lysosomes, where it carries out the ceramide hydrolysis process.
Deficiency in ASAH2 activity can lead to the accumulation of ceramides, which may disrupt cellular signaling and contribute to disease development.
ASAH2 gene expression can be regulated by various factors, including transcription factors, epigenetic modifications, and signaling pathways.
Mutations in the ASAH2 gene have been associated with a rare form of hereditary sensory and autonomic neuropathy (HSAN) called HSAN1C.
Yes, ASAH2 is ubiquitously expressed in various tissues throughout the body.
Customer Reviews (3)
Write a reviewIt reliably and accurately detects and quantifies target molecules, allowing for precise measurement of analytes in my samples.
I highly recommend the ASAH2 Protein for its outstanding performance in ELISA assays.
The sensitivity and specificity of the ASAH2 Protein have consistently delivered robust and consistent results, enhancing the efficiency and accuracy of my experimental workflows.
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