bcap31
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  • Official Full Name
  • B-cell receptor-associated protein 31
  • Background
  • This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in the caspase 8-mediated apoptosis. Microdeletions in this gene are associated with the contiguous ABCD1/DXS1375E deletion syndrome. Two pseudogenes have been identified on chromosome 16. Alternatively spliced transcript variants encoding distinct isoforms have been described although the biological validity of some of the variants has not been determined.
  • Synonyms
  • CAP31; B-cell receptor-associated protein 31; CDM; BAP31; 6C6-AG; DXS1357E; BCR-associated protein 31; 6C6-AG tumor-associated antigen; Protein CDM; p28; OTTHUMP00000025977; OTTHUMP00000025978; OTTHUMP00000025979; OTTHUMP00000025981; OTTHUMP00000025983; BCR-associated
Cat.#:BCAP31-10163HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BCAP31, GST-tagged
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Cat.#:BCAP31-118HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BCAP31 Protein, GST-tagged
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Cat.#:BCAP31-119HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BCAP31 Protein, GST-tagged
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Cat.#:BCAP31-2320MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BCAP31 Protein
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Cat.#:BCAP31-10444ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BCAP31
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Cat.#:BCAP31-8499HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BCAP31 293 Cell Lysate
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Involved Pathway

BCAP31 involved in several pathways and played different roles in them. We selected most pathways BCAP31 participated on our site, such as Apoptosis, Apoptotic cleavage of cellular proteins, Apoptotic execution phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCAP31 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Apoptosis
IL1RAP; SATB1; HMGB2; NMT1; CASP12; DBNLA; BCL2A; IRF2; DAPK1; GZMC
Apoptotic cleavage of cellular proteins
CLSPN; LMNB1; PLECA; DSG2; CASP6L2; BCAP31; SPNA2; PLEC; PTBP3; VIML
Apoptotic execution phase
PLEC; PLECA; SATB1; CASP8L1; HIST1H1C; OCLN; HMGB2; STK24B; GAS2; HIST1H1E
Programmed Cell Death
ADD1; STK24B; HMGB2; RIPK3; STK24; DIABLOA; GZMF; GAS2; DSG3; DBNL
Protein processing in endoplasmic reticulum
EIF2AK2; MAPK10; ATF4B1; SSR1; MAN1C1; HSPA8; PDIP5; HSPA1L; DNAJB1B; EIF2S1B

Protein Function

BCAP31 has several biochemical functions, for example, MHC class I protein binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BCAP31 itself. We selected most functions BCAP31 had, and list some proteins which have the same functions with BCAP31. You can find most of the proteins on our site.
Function
Related Protein
Function MHC class I protein binding
Related Protein DERL1; CD244; ATP5A1; HLA-E; PILRB; BCAP31; TUBB4B; PILRB2; TAPBP; LILRB1
Function protein binding
Related Protein SAFB2; GJD3; BRK1; MED23; SREK1; BHLHE40; PKM2; NXT1; HDLBP; APIP
Function protein complex binding
Related Protein DRD1; HNF1B; LCA5; VAMP2; Cel; KLHL8; CDK4; CPD; KRT8; LCK

Interacting Protein

BCAP31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCAP31 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCAP31.
SEC61B; TRAM1; FIS1

BCAP31 Related Articles

van de Kamp, JM; Errami, A; et al. Genotype-phenotype correlation of contiguous gene deletions of SLC6A8, BCAP31 and ABCD1. CLINICAL GENETICS 87:141-147(2015).
Calhoun, ARUL; Raymond, GV; et al. Distal Xq28 Microdeletions: Clarification of the Spectrum of Contiguous Gene Deletions Involving ABCD1, BCAP31, and SLC6A8 with a New Case and Review of the Literature. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2613-2617(2014).