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Official Full Name B-cell receptor-associated protein 31
Background This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in the caspase 8-mediated apoptosis. Microdeletions in this gene are associated with the contiguous ABCD1/DXS1375E deletion syndrome. Two pseudogenes have been identified on chromosome 16. Alternatively spliced transcript variants encoding distinct isoforms have been described although the biological validity of some of the variants has not been determined.
Synonyms CAP31; B-cell receptor-associated protein 31; CDM; BAP31; 6C6-AG; DXS1357E; BCR-associated protein 31; 6C6-AG tumor-associated antigen; Protein CDM; p28; OTTHUMP00000025977; OTTHUMP00000025978; OTTHUMP00000025979; OTTHUMP00000025981; OTTHUMP00000025983; BCR-associated
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BCAP31-10163H Recombinant Human BCAP31, GST-tagged E.coli GST
    Human BCAP31-118H Recombinant Human BCAP31 Protein, GST-tagged Wheat Germ GST
    Human BCAP31-119H Recombinant Human BCAP31 Protein, GST-tagged Wheat Germ GST
    Human BCAP31-8499HCL Recombinant Human BCAP31 293 Cell Lysate HEK293 N/A
    Mouse BCAP31-2320M Recombinant Mouse BCAP31 Protein Mammalian Cell His
    Zebrafish BCAP31-10444Z Recombinant Zebrafish BCAP31 Mammalian Cell His

    BCAP31 involved in several pathways and played different roles in them. We selected most pathways BCAP31 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCAP31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Apoptosis PLEC; BADB; PIK3R5; AIFM1; IL1R1; CLSPN; XIAP; RIPK1; TRP53; STK26
    Apoptotic cleavage of cellular proteins ADD1; LMNB1; CTNNB1; DBNL; BMX; CTNNB2; SPNA2; PKP1; VIML; CASP6L2
    Apoptotic execution phase DFFA; BCAP31; CTNNB1; CASP6L1; STK24B; CASP6L2; VIML; PANK1A; DNM1L; GAS2
    Programmed Cell Death HMGB2A; DSP; DIABLOB; GZMC; STK26; DSG1; GAS2; DAPK1; DNM1L; STK24
    Protein processing in endoplasmic reticulum UBE2E2; AMFR; MAP3K5; DNAJC10; SAR1AB; SVIP; CAPN2; HSPA1L; HSPA6; CAPN1B

    BCAP31 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by BCAP31 itself. We selected most functions BCAP31 had, and list some proteins which have the same functions with BCAP31. You can find most of the proteins on our site.

    Function Related Protein
    MHC class I protein binding PILRB2; BCAP31; ATP5A1; LILRB2; TAPBP; HLA-E; TUBB4B; CD8B; ATP5B; TUBB
    protein binding DEDD; HNRNPR; SUMO3; NR1H4; PIAS1; TTPA; C2orf63; KLK4; PEF1; ETV5
    protein complex binding NDUFA8; COG2; PPP4C; UGT1A6A; HCLS1; UGT1A6B; ULK1; ABI1; CPS1; ERCC6

    BCAP31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCAP31 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCAP31.

    SEC61B; TRAM1; FIS1

    van de Kamp, JM; Errami, A; et al. Genotype-phenotype correlation of contiguous gene deletions of SLC6A8, BCAP31 and ABCD1. CLINICAL GENETICS 87:141-147(2015).
    Calhoun, ARUL; Raymond, GV; et al. Distal Xq28 Microdeletions: Clarification of the Spectrum of Contiguous Gene Deletions Involving ABCD1, BCAP31, and SLC6A8 with a New Case and Review of the Literature. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2613-2617(2014).

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