Recombinant Full Length Human BCAP31 Protein, C-Flag-tagged

• Cat.No.: BCAP31-1947HFL
• Product Overview: Recombinant Full Length Human BCAP31 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 27.8 kDa
• AA Sequence: MSLQWTAVATFLYAEVFVVLLLCIP FISPKRWQKIFKSRLVELLVSYGNT FFVVLIVILVLLVIDAVREI REYDDVTEKVNLQNNPGAMEHFHMK LFRAQRNLYIAGFSLLLSFLLRRLV TLISQQATLLASNEAFKKQA ESASEAAKKYMEENDQLKKGAAVDG GKLDVGNAEVKLEEENRSLKADLQK LKDELASTKQKLEKAENQVL AMRKQSEGLTKEYDRLLEEHAKLQA AVDGPMDKKEE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: BCAP31 B cell receptor associated protein 31 [ Homo sapiens (human) ]
• Official Symbol: BCAP31
• Synonyms: CDM; DDCH; BAP31; 6C6-AG; DXS1357E
• Gene ID: 10134
• mRNA Refseq: NM_001139441.1
• Protein Refseq: NP_001132913.1
• MIM: 300398
• UniProt ID: P51572