|Official Full Name||bone morphogenetic protein 6|
|Background||The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.|
|Synonyms||BMP6; bone morphogenetic protein 6; vegetal related growth factor (TGFB related) , VGR; VGR1; BMP-6; BMP6_HUMAN; Bone Morphogenic Protein 6; Decapentaplegic vegetal related; DVR6; HGNC:12686; TGFB related vegetal related growth factor; Transforming growth factor beta; Vegetal related (TGFB related) cytokine; Vg related sequence; VG-1-R; VG-1-related protein; VGR-1; OTTHUMP00000016006; Vg1-related sequence; vegetal-related (TGFB related) cytokine; vegetal related growth factor (TGFB-related); VGR|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
BMP6 involved in several pathways and played different roles in them. We selected most pathways BMP6 participated on our site, such as TGF-beta signaling pathway, Hippo signaling pathway, Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|TGF-beta signaling pathway||RPS6KB2; CHRD; PPP2R1A; ID2A; BMPR1BA; CUL1; RHOA; FSTA; BMP5; CHD|
|Hippo signaling pathway||CCND2; WNT9A; SAV1; FGF1; NF2; PARD3; PPP2R2C; YAP1; PPP2CA; ID2|
|Ovarian steroidogenesis||PLA2G4A; CYP2J6; STAR; PRKACA; HSD3B5; CYP2J5; BMP6; ALOX5; PLA2G4D; INSR|
BMP6 has several biochemical functions, for example, BMP receptor binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP6 itself. We selected most functions BMP6 had, and list some proteins which have the same functions with BMP6. You can find most of the proteins on our site.
|BMP receptor binding||BMP6; PYCARD; BMP8A; BMP2; BMP7B; BMP2B; BMP8B; BMP7A; BMP5; BMP7|
|cytokine activity||WNT1; GPI1; TNFSF12; IFNA5; NDR2; BMP8B; GDF11; CXCL9; TGFB2; IFNG1-1|
|growth factor activity||CD320; FGF16; BMP16; PSPN; TGFB1; BMP2B; BMP10; IL11; LFT2; CNTF|
|protein heterodimerization activity||BCL2; HIF1A; HOMER2; VAPB; BCL2L1; CYBA; USF2; NFE2L2A; HIST1H2BB; BMP7A|
|transforming growth factor beta receptor binding||GDF1; BMP6; BMP15; GDF2; GDF6; BMP7; FKBP1A; LFT2; NDR1; BMP2|
BMP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP6.