Active Recombinant Mouse Bmp6
Cat.No. : | Bmp6-28M |
Product Overview : | Recombinant Mouse Bmp6(Ser372-His510) was expressed in CHO Cells. |
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Description : | Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. The protein encoded by this gene is a member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce the growth of bone and cartilage. BMP6 is able to induce all osteogenic markers in mesenchymal stem cells. |
Source : | CHO Cells |
Species : | Mouse |
Predicted N Terminal : | Ser372 |
Form : | Disulfide-linked homodimer. Lyophilized from a 0.2 μm filtered solution in HCl. |
Bio-activity : | Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is typically 0.1 - 0.4 μg/mL. |
Molecular Mass : | Predicted Molecular Mass: 15.5 kDaSDS-PAGE: 18 kDa, reducing conditions |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 °C as supplied.1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70 °C under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 200 μg/mL in 4mM HCl. |
Tag : | Non |
Protein length : | Ser372-His510 |
Gene Name : | Bmp6 bone morphogenetic protein 6 [ Mus musculus (house mouse) ] |
Official Symbol : | Bmp6 |
Synonyms : | Bmp6; Vgr1; D13Wsu115e; bone morphogenetic protein 6; BMP-6; VG-1-related protein |
Gene ID : | 12161 |
mRNA Refseq : | NM_007556 |
Protein Refseq : | NP_031582 |
UniProt ID : | P20722 |
Chromosome Location : | 13 A3.3; 13 18.15 cM |
Pathway : | Endochondral Ossification; Hippo signaling pathway; Ovarian steroidogenesis |
Function : | BMP receptor binding; cytokine activity; growth factor activity |
Products Types
◆ Recombinant Protein | ||
BMP6-656R | Recombinant Rat BMP6 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP6-16H | Recombinant Active Human BMP6 Protein, His-tagged(C-ter) | +Inquiry |
BMP6-4368H | Recombinant Human BMP6 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP6-015H | Active Recombinant Human BMP6 Protein | +Inquiry |
Bmp6-10523M | Recombinant Mouse Bmp6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
BMP6-8430HCL | Recombinant Human BMP6 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe BMP6 protein has proven to be an invaluable tool in protein electron microscopy (EM) structure analysis.
The BMP6 protein is of exceptional quality, making it an ideal choice to meet my experimental needs.
This protein demonstrates great performance in WB assays, providing accurate and reliable results that are crucial for protein analysis.
Q&As (5)
Ask a questionYes, there are several ongoing clinical trials investigating the therapeutic applications of BMP6, including its use in bone regeneration and the treatment of musculoskeletal disorders.
Yes, BMP6 is often used in combination with other growth factors and scaffolds to enhance its regenerative potential, especially in tissue engineering applications.
No, BMP6's influence extends beyond bone health. It has been implicated in various cellular processes, including iron homeostasis, and its therapeutic potential is being explored in multiple medical fields.
BMP6 has therapeutic potential in treating bone disorders, such as non-union fractures and osteoporosis. Its ability to stimulate bone formation makes it a valuable candidate for regenerative medicine.
BMP6 can be administered both locally and systemically, depending on the therapeutic goals. Local administration is often preferred for targeted effects, such as bone regeneration at a specific site.
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