Active Recombinant Mouse Bmp6

Cat.No. : Bmp6-28M
Product Overview : Recombinant Mouse Bmp6(Ser372-His510) was expressed in CHO Cells.
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Description : Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. The protein encoded by this gene is a member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce the growth of bone and cartilage. BMP6 is able to induce all osteogenic markers in mesenchymal stem cells.
Source : CHO Cells
Species : Mouse
Predicted N Terminal : Ser372
Form : Disulfide-linked homodimer. Lyophilized from a 0.2 μm filtered solution in HCl.
Bio-activity : Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is typically 0.1 - 0.4 μg/mL.
Molecular Mass : Predicted Molecular Mass: 15.5 kDaSDS-PAGE: 18 kDa, reducing conditions
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 °C as supplied.1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 200 μg/mL in 4mM HCl.
Gene Name : Bmp6 bone morphogenetic protein 6 [ Mus musculus (house mouse) ]
Official Symbol : Bmp6
Synonyms : Bmp6; Vgr1; D13Wsu115e; bone morphogenetic protein 6; BMP-6; VG-1-related protein
Gene ID : 12161
mRNA Refseq : NM_007556
Protein Refseq : NP_031582
UniProt ID : P20722
Chromosome Location : 13 A3.3; 13 18.15 cM
Pathway : Endochondral Ossification; Hippo signaling pathway; Ovarian steroidogenesis
Function : BMP receptor binding; cytokine activity; growth factor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any ongoing clinical trials involving BMP6? 01/27/2022

Yes, there are several ongoing clinical trials investigating the therapeutic applications of BMP6, including its use in bone regeneration and the treatment of musculoskeletal disorders.

Can BMP6 be used in conjunction with other growth factors? 10/09/2017

Yes, BMP6 is often used in combination with other growth factors and scaffolds to enhance its regenerative potential, especially in tissue engineering applications.

Is BMP6 only relevant for bone-related conditions? 11/01/2016

No, BMP6's influence extends beyond bone health. It has been implicated in various cellular processes, including iron homeostasis, and its therapeutic potential is being explored in multiple medical fields.

How does BMP6 contribute to the treatment of bone disorders? 08/08/2016

BMP6 has therapeutic potential in treating bone disorders, such as non-union fractures and osteoporosis. Its ability to stimulate bone formation makes it a valuable candidate for regenerative medicine.

Can BMP6 be administered systemically or is it site-specific? 01/15/2016

BMP6 can be administered both locally and systemically, depending on the therapeutic goals. Local administration is often preferred for targeted effects, such as bone regeneration at a specific site.

Customer Reviews (3)

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08/14/2022

    The BMP6 protein has proven to be an invaluable tool in protein electron microscopy (EM) structure analysis.

    11/02/2020

      The BMP6 protein is of exceptional quality, making it an ideal choice to meet my experimental needs.

      10/15/2019

        This protein demonstrates great performance in WB assays, providing accurate and reliable results that are crucial for protein analysis.

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