Active Recombinant Mouse Bmp6

• Cat.No.: Bmp6-28M
• Product Overview: Recombinant Mouse Bmp6(Ser372-His510) was expressed in CHO Cells.

Specification

• Description: Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. The protein encoded by this gene is a member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce the growth of bone and cartilage. BMP6 is able to induce all osteogenic markers in mesenchymal stem cells.
• Source: CHO Cells
• Species: Mouse
• Predicted N Terminal: Ser372
• Form: Disulfide-linked homodimer. Lyophilized from a 0.2 μm filtered solution in HCl.
• Bio-activity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is typically 0.1 - 0.4 μg/mL.
• Molecular Mass: Predicted Molecular Mass: 15.5 kDaSDS-PAGE: 18 kDa, reducing conditions
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 °C as supplied.1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 200 μg/mL in 4mM HCl.

Gene Information

• Gene Name: Bmp6 bone morphogenetic protein 6 [ Mus musculus (house mouse) ]
• Official Symbol: Bmp6
• Synonyms: Bmp6; Vgr1; D13Wsu115e; bone morphogenetic protein 6; BMP-6; VG-1-related protein
• Gene ID: 12161
• mRNA Refseq: NM_007556
• Protein Refseq: NP_031582
• UniProt ID: P20722
• Chromosome Location: 13 A3.3; 13 18.15 cM
• Pathway: Endochondral Ossification; Hippo signaling pathway; Ovarian steroidogenesis
• Function: BMP receptor binding; cytokine activity; growth factor activity