c
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  • Official Full Name
  • chib
  • Background
  • Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • C; chib; C22orf2, chromosome 22 open reading frame 2 , PGEA1, PKD2 interactor, golgi and endoplasmic reticulum associated 1; protein chibby homolog 1; Cby; Chibby; PIGEA 14; PIGEA14; C22orf2; Cytosolic leucine rich protein; HRIHFB2025; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; Protein Chibby; OTTHUMP00000198875; OTTHUMP00000198876; OTTHUMP00000198878; ARPP-binding protein; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; PKD2 interactor, golgi and end; arb1; PGEA1; PIGEA-14; HS508I15A
Cat.#:C-1809JTag:N/A
Source (Host):E. coliSpecies:JEV
Product nameRecombinant JEV C Protein
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Cat.#:C-1810RTag:N/A
Source (Host):E. coliSpecies:RuV
Product nameRecombinant RuV (Strain TO-336) C Protein
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Cat.#:C-1811YTag:N/A
Source (Host):E. coliSpecies:YEV
Product nameRecombinant YEV C Protein
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Cat.#:C-30019THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human C, His-tagged
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Cat.#:C-2556MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse C Protein
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Cat.#:C-1038RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat C Protein
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Cat.#:C -74HTag:N/A
Source (Host):E. coliSpecies:HBV
Product nameRecombinant Hepatitis B Virus C protein
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Cat.#:C -75HTag:His
Source (Host):E. coliSpecies:HBV
Product nameRecombinant Hepatitis B Virus C protein, His-tagged
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Cat.#:C -76HTag:His
Source (Host):E. coliSpecies:HBV
Product nameRecombinant Hepatitis B Virus C protein, His-tagged
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Cat.#:C -77HTag:N/A
Source (Host):E. coliSpecies:HBV
Product nameRecombinant Hepatitis B Virus C protein
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Cat.#:C -78HTag:GST
Source (Host):E. coliSpecies:HBV
Product nameRecombinant Hepatitis B Virus C protein, GST-tagged
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Cat.#:C-1506STag:His
Source (Host):E. coli or YeastSpecies:Streptomyces phage phiC31
Product nameRecombinant Streptomyces phage phiC31 C protein, His-tagged
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Cat.#:C-313VTag:N/A
Source (Host):E. coliSpecies:SARS
Product nameRecombinant SARS Nucleocapsid core Protein
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Cat.#:C-314VTag:N/A
Source (Host):E. coliSpecies:SARS
Product nameRecombinant SARS Nucleocapsid core Protein
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Cat.#:C-393VTag:N/A
Source (Host):E. coliSpecies:Measles Virus
Product nameRecombinant Measles Virus Non-Structural C Protein
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Cat.#:C-472VTag:N/A
Source (Host):E. coliSpecies:Rubella Virus
Product nameRecombinant Rubella Virus Capsid (C) Protein
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Cat.#:C-477VTag:N/A
Source (Host):E. coliSpecies:SARS
Product nameRecombinant SARS Associated Coronavirus Nucleocapsid C Protein
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Cat.#:C-485DTag:His
Source (Host):E. coliSpecies:Dengue
Product nameRecombinant Dengue virus Capsid protein, His-tagged
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Cat.#:C-733VTag:His
Source (Host):E. coliSpecies:DENV
Product nameRecombinant DENV (Strain New Guinea C) C Protein, His-tagged
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Cat.#:CDE017Tag:His
Source (Host):E. coliSpecies:HBV
Product nameRecombinant HBeAg protein, His-tagged
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Cat.#:HBcAg-19HTag:N/A
Source (Host):Pichia pastorisSpecies:HBV
Product nameRecombinant Hepatitis B Virus C protein
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Cat.#:HCV-01Tag:His
Source (Host):E. coliSpecies:HCV
Product nameRecombinant HCV Core protein, His-tagged
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Cat.#:HCV-02Tag:N/A
Source (Host):E. coliSpecies:HCV
Product nameRecombinant HCV Core protein
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Involved Pathway

C involved in several pathways and played different roles in them. We selected most pathways C participated on our site, such as Deactivation of the beta-catenin transactivating complex, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Deactivation of the beta-catenin transactivating complex
ASH2L; TLE4; SOX7; CBY1; C; PYGO2; TLE1; RBBP5; TLE2; BCL9L
Signal Transduction
RHPN2; CDC73; RSPO4; APOA4B.2; SKIA; PMEPA1; PNOCB; AMOTL2; IFT52; FGD4A
Signaling by Wnt
DACT1; SOX9B; LGR6; LGR5; BCL9L; USP34; RNF43; ROR2; RNF146; GPR177
TCF dependent signaling in response to WNT
SRY; RSPO1; BCL9; SOX13; TNKS2; CCDC88C; SOX4A; SOX32; SOX6; KREMEN1

Protein Function

C has several biochemical functions, for example, beta-catenin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C itself. We selected most functions C had, and list some proteins which have the same functions with C. You can find most of the proteins on our site.
Function
Related Protein
Function beta-catenin binding
Related Protein CTNNBIP1; NF2; FAM123B; DACT2; CD2AP; ESR1; EP300; MED12L; ASH2L; LZTS2A
Function identical protein binding
Related Protein BCL2L1; BAG2; EID3; TRP63; CD74; WAS; DNM1; GCC2; KCNH2; VPS41

Interacting Protein

C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C here. Most of them are supplied by our site. Hope this information will be useful for your research of C.
Hmga2

C Related Articles

Yang, YR; Feng, JD; et al. Immune Responses to a Recombinant Rv0057-Rv1352 Fusion Protein of Mycobacterium tuberculosis. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:39-48(2015).
Khosravi-Farsani, S; Amidi, F; et al. Isolation and Enrichment of Mouse Female Germ Line Stem Cells. CELL JOURNAL 16:406-415(2015).

C Related Gene Family

GPCRs IL TGF Immunoglobulins TNF Kinesins (KIF) BCL2 Gene Family WNT