|Official Full Name||chib|
|Background||Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||C; chib; C22orf2, chromosome 22 open reading frame 2 , PGEA1, PKD2 interactor, golgi and endoplasmic reticulum associated 1; protein chibby homolog 1; Cby; Chibby; PIGEA 14; PIGEA14; C22orf2; Cytosolic leucine rich protein; HRIHFB2025; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; Protein Chibby; OTTHUMP00000198875; OTTHUMP00000198876; OTTHUMP00000198878; ARPP-binding protein; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; PKD2 interactor, golgi and end; arb1; PGEA1; PIGEA-14; HS508I15A|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
C involved in several pathways and played different roles in them. We selected most pathways C participated on our site, such as Deactivation of the beta-catenin transactivating complex, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Deactivation of the beta-catenin transactivating complex||SOX4A; SOX9B; TLE1; BCL9L; PYGO1; SOX13; CBY1; SOX6; TLE3B; TLE3|
|Signal Transduction||ANXA1A; WNT8-2; PTGDR2; LEO1; ARHGAP29B; RIT2; DEPDC1B; ARHGAP1; ARHGAP28; EDNRAB|
|Signaling by Wnt||ZNRF3; CCDC88C; CDC73; C; PYGO1; USP34; HECW1B; TLE3B; WLS; AES|
|TCF dependent signaling in response to WNT||WNT8-2; LGR4; LEO1; CBY1; SOX4B; SOX7; ASH2L; TNKS2; RSPO1; DACT1|
C has several biochemical functions, for example, beta-catenin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C itself. We selected most functions C had, and list some proteins which have the same functions with C. You can find most of the proteins on our site.
|beta-catenin binding||LZIC; HDAC6; CDH2; TCF7L2; DVL3; EP300; PSEN1; CARM1; GLI3; RORA|
|identical protein binding||CSNK2B; RAF1; CLDN9; EID3; CPT1A; HGF; CLDN11; NDE1; CCL4; PIP4K2C|
C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C here. Most of them are supplied by our site. Hope this information will be useful for your research of C.