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Official Full Name Carbonic anhydrase II
Background Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye.
Synonyms CA 2; CA II; CA-II; CA2; CAC; CAH2_HUMAN; CAII; Car 2; Carbonate dehydratase II; Carbonic anhydrase 2; Carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; Carbonic dehydratase; EC; IUB:; CA, HUMAN LIVER; CA1, BOVINE ERYTHROCYTES; CARBONATE DEHYDRATASE; CARBONATE HYDRO-LYASE; CARBONIC ANHYDRASE; PANCREAS, BOVINE; carbonic anhydrase from bovine erythro-cytes; Dehydratase, carbonate; TDX-02; Car-2; Ltw-5; Lvtw-5; AI131712; Car2
    • Species :
    • Chicken
    • Dog
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Sheep
    • Zebrafish
    • Source :
    • Dog
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Mouse
    • Rabbit
    • Rat
    • Rhesus monkey
    • Sheep
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CA2-201H Recombinant Human CA2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human CA2-354H Recombinant Human CA2 protein, His-tagged HEK293 His
    Human CA2-0237H Recombinant Human CA2 Protein E.coli N/A
    Human CA2-0238H Recombinant Human CA2 Protein, GST-Tagged Wheat Germ GST
    Human CA2-10619H Recombinant Human CA2, GST-tagged E.coli GST
    Human CA2-1114H Recombinant Human CA2 protein, His-tagged E.coli His
    Human CA2-144H Recombinant Human Carbonic Anhydrase II E.coli N/A
    Human CA2-219H Recombinant Human CA2 E.coli N/A
    Human CA2-220H Recombinant Human CA2, C13&N15-labeled HEK293 N/A
    Human CA2-27265TH Recombinant Human CA2 E.coli N/A
    Human CA2-30H Native Human Carbonic Anhydrase II (CA2) Protein Human N/A
    Human CA2-7915HCL Recombinant Human CA2 293 Cell Lysate HEK293 N/A
    Human CA2-864H Recombinant Human CA2, His tagged E.coli His
    Mouse CA2-31M Native Mouse Carbonic Anhydrase II (CA2) Protein Mouse N/A
    Mouse Car2-1191M Recombinant Mouse Carbonic Anhydrase 2, His-tagged Mouse His
    Mouse CAR2-2718M Recombinant Mouse CAR2 Protein Mammalian Cell His
    Mouse Car2-886M Recombinant Mouse Car2 Protein, His-tagged E.coli His
    Rat CA2-1057R Recombinant Rat CA2 Protein Mammalian Cell His
    Rat CA2-33R Native Rat Carbonic Anhydrase II (CA2) Protein Rat N/A
    Rhesus monkey CA2-35R Native Rhesus monkey Carbonic Anhydrase II (CA2) Protein Rhesus monkey N/A
    Rhesus Macaque CA2-597R Recombinant Rhesus monkey CA2 Protein, His-tagged Mammalian Cell His
    Rhesus monkey CA2-7678R Recombinant Rhesus monkey CA2 protein, His-tagged E.coli His
    Dog CA2-29D Native Dog Carbonic Anhydrase II (CA2) Protein Dog N/A
    Rabbit CA2-34R Native Rabbit Carbonic Anhydrase II (CA2) Protein Rabbit N/A
    Chicken CA2-6869C Recombinant Chicken CA2 Mammalian Cell His
    Chicken CA2-7676C Recombinant Chicken CA2 protein, His-tagged E.coli His
    Zebrafish CA2-9899Z Recombinant Zebrafish CA2 Mammalian Cell His
    Sheep CA2-32S Native Sheep Carbonic Anhydrase II (CA2) Protein Sheep N/A

    CA2 involved in several pathways and played different roles in them. We selected most pathways CA2 participated on our site, such as Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nitrogen metabolism CA13; CAR3; GLUL; CA4B; CA3; GLUD2; Car2; CA7; CAR15; GLUD1A
    Proximal tubule bicarbonate reclamation ATP1A4; ATP1B2; ATP1A1; ATP1A2; FXYD2; SLC38A3; Car2; SLC4A4; CA2; SLC25A10
    Collecting duct acid secretion ATP6V0A1; ATP6V1E1; SLC12A7; ATP6V0E2; ATP6V1D; ATP6V1E2; ATP6V0A4; CA2; ATP4A; ATP6V1F
    Gastric acid secretion PRKCA; PRKACG; ATP1A3; MYLK; HRH2; MYLK3; KCNJ10; GNAS; KCNJ15; CAMK2D
    Pancreatic secretion BST1; ITPR1; AMY2B; Adcy4; PLA2G10; PRKCB; CLCA2; TRPC1; GNAS; Cel
    Bile secretion ABCB4; CYP7A1; ATP1B3; SLC22A1; ABCG2; SLCO1B2; CYP3A4; ATP1A4; SULT2A1; GNAS

    CA2 has several biochemical functions, for example, arylesterase activity, carbonate dehydratase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA2 itself. We selected most functions CA2 had, and list some proteins which have the same functions with CA2. You can find most of the proteins on our site.

    Function Related Protein
    arylesterase activity APMAP; Car2; CA2; PON1; C20orf3; CA1; CAR1; PON3; PON2
    carbonate dehydratase activity CA15C; Car9; CAR3; CA4; Car2; CA6; CA8; CA4B; CA5; CA3
    protein binding MED6; MEIS1; TNNI3K; FASTK; MAPK4; BTN2A2; HNRNPA2B1; NFKBIA; NUMB; RNMT
    zinc ion binding TRIM2; POLR2K; TRIM38; ERI2; LMX1A; PEX2; FHL3B; KNG1; RNF13; SORD

    CA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA2.

    Cdk1; PCNA; USP42; ANKZF1; PTCHD2

    Kale, SL; Arora, N; et al. Per a 10 activates human derived epithelial cell line in a protease dependent manner via PAR-2. IMMUNOBIOLOGY 220:525-532(2015).
    Zhang, Y; Li, H; et al. Melatonin-mediated inhibition of Purkinje neuron P-type Ca2+ channels in vitro induces neuronal hyperexcitability through the phosphatidylinositol 3-kinase-dependent protein kinase C delta pathway. JOURNAL OF PINEAL RESEARCH 58:321-334(2015).

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