|Official Full Name||carbonic anhydrase IV|
|Background||Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport.|
|Synonyms||CA4; carbonic anhydrase IV; retinitis pigmentosa 17 (autosomal dominant) , RP17; carbonic anhydrase 4; CAIV; Car4; CA IV; Carbonate dehydratase IV; Carbonic dehydratase; Carbonic dehydratase IV; EC 188.8.131.52; Retinitis pigmentosa 17 (autosomal dominant); RP17; CA-IV; AW456718|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CA4 involved in several pathways and played different roles in them. We selected most pathways CA4 participated on our site, such as Nitrogen metabolism, Proximal tubule bicarbonate reclamation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Nitrogen metabolism||CA8; GLUD2; CAR3; CA2; GLUD1B; GLUD1; CA4B; CAR5A; GLUL; CA4|
|Proximal tubule bicarbonate reclamation||PCK1; ATP1B2; FXYD2; ATP1B1; ATP1A2; CA2; SLC4A4; ATP1B4; ATP1A3; SLC38A3|
CA4 has several biochemical functions, for example, carbonate dehydratase activity, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA4 itself. We selected most functions CA4 had, and list some proteins which have the same functions with CA4. You can find most of the proteins on our site.
|carbonate dehydratase activity||CAR7; CA14; CA13; Car9; CA3; CAR5A; Car2; Car8; CAR6; Car12|
|protein binding||SEMA3E; ORC6L; TBX15; BAK1; TRAF3IP3; TXN; CRYGC; CALCOCO2; EPRS; ZMAT3|
|zinc ion binding||RARGB; RNF144AB; EDEM3; CALR; AKAP8; CPM; NR4A1; DEF8; TRIM68; BRAP|
CA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA4.
SLC4A4; PRDX2; PIH1D1; HTT