CD1D Protein, CD1d molecule

CD1D

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CD1D

Official Full Name CD1d molecule
Background This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related;to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1;proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.;The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are;thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by;this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.
Synonyms CD1D; CD1d molecule; CD1d antigen , CD1D antigen, d polypeptide; antigen-presenting glycoprotein CD1d; R3G1; thymocyte antigen CD1D; CD1D antigen, d polypeptide; T-cell surface glycoprotein CD1d; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D; R3; CD1A; MGC34622
    • Species :
    • Human
    • Rabbit
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD1D & B2M-001HCL Recombinant Human CD1D & B2M cell lysate Human Cell N/A
    Human CD1D & B2M-250H Recombinant Human CD1D(Met1-Ser301)& B2M(Met1-Met119) protein, His-tagged HEK293 His
    Human CD1D-10920H Recombinant Human CD1D, His-tagged E.coli His
    Human CD1D-2188H Recombinant Human CD1D, His tagged Human Cell His
    Human CD1D-231H Recombinant Human CD1D Protein, His-tagged Insect Cell His
    Human CD1D-2479HCL Recombinant Human CD1D cell lysate Human Cell N/A
    Human CD1D-27107TH Recombinant Human CD1D Wheat Germ N/A
    Human CD1D-828H Recombinant Human CD1D Protein, Fc-tagged HEK293 Fc
    Rhesus Macaque CD1D-723R Recombinant Rhesus monkey CD1D Protein, His-tagged Mammalian Cell His
    Rabbit CD1D-3515S Recombinant Sylvilagus floridanus (Cottontail rabbit) CD1D, His-tagged E.Coli or Yeast His

    CD1D involved in several pathways and played different roles in them. We selected most pathways CD1D participated on our site, such as Hematopoietic cell lineage, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD1D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hematopoietic cell lineage CD37; IL1R2; CD1D2; CD22; CD7; CD44; IL11RA; CD2; CD1C; HLA-DRB5
    Amoebiasis PLCB1; RAB7A; LAMB2; SERPINB9; GNA15; ITGB2L; RAB7; PIK3R2; TLR2; LAMC2

    CD1D has several biochemical functions, for example, beta-2-microglobulin binding, cell adhesion molecule binding, endogenous lipid antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD1D itself. We selected most functions CD1D had, and list some proteins which have the same functions with CD1D. You can find most of the proteins on our site.

    Function Related Protein
    beta-2-microglobulin binding CD1D; CD1B; HLA-E; CD1D2; CD1d1; HFE; CD1C; CD1E; CD1A; HLA-A
    cell adhesion molecule binding AMICA1; ADAM8; NLGN1; FGFR1; PVRL2L; NRXN1; CD1d1; PTPRD; DSG2; FGG
    endogenous lipid antigen binding CD1C; CD1D; CD1D2; CD1A; CD1B; CD1d1; CD1E
    exogenous lipid antigen binding CD1B; CD1D2; CD1E; CD1D; CD1C; CD1A; CD1d1
    histone binding HIST1H4I; DAXX; APBB1; DTX3L; UHRF2; HIST1H3H; HIST1H3I; HIST2H3C1; BAZ2A; NOC2L
    lipid antigen binding CD1D; CD1d1
    lipopeptide binding CD1B; CD1D; CD1A; CD1E; CD1D2; CD1d1; TLR6; CD1C
    receptor activity KLRB1B; GPA33; CD93; GRIN2A; MED24; NRP2; TREML2; LILRA2; IL10RA; P2RY2

    CD1D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD1D here. Most of them are supplied by our site. Hope this information will be useful for your research of CD1D.

    Rosales, C; Tang, DM; et al. CD1d serves as a surface receptor for oxidized cholesterol induction of peroxisome proliferator-activated receptor-gamma. ATHEROSCLEROSIS 239:224-231(2015).
    Matsuda, T; Yanase, S; et al. The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation. IMMUNITY & AGEING 12:-(2015).

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