cd1d
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  • Official Full Name
  • CD1d molecule
  • Background
  • This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related;to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1;proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.;The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are;thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by;this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.
  • Synonyms
  • CD1D; CD1d molecule; CD1d antigen , CD1D antigen, d polypeptide; antigen-presenting glycoprotein CD1d; R3G1; thymocyte antigen CD1D; CD1D antigen, d polypeptide; T-cell surface glycoprotein CD1d; differentiation antigen CD1-alpha-3; HMC class I antigen-like glycoprotein CD1D; R3; CD1A; MGC34622
Cat.#:CD1D-231HTag:His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human CD1D Protein, His-tagged
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Cat.#:CD1D & B2M-250HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1D(Met1-Ser301)& B2M(Met1-Met119) protein, His-tagged
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Cat.#:CD1D-10920HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD1D, His-tagged
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Cat.#:CD1D-2188HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1D, His tagged
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Cat.#:CD1D-27107THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CD1D
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Cat.#:CD1D-828HTag:Fc
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CD1D Protein, Fc-tagged
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Cat.#:CD1D-723RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD1D Protein, His-tagged
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Cat.#:CD1D-3515STag:His
Source (Host):Mammalian CellsSpecies:Rabbit
Product nameRecombinant Sylvilagus floridanus (Cottontail rabbit) CD1D, His-tagged
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Cat.#:CD1D & B2M-001HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1D & B2M cell lysate
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Cat.#:CD1D-2479HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD1D cell lysate
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Involved Pathway

CD1D involved in several pathways and played different roles in them. We selected most pathways CD1D participated on our site, such as Hematopoietic cell lineage, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD1D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hematopoietic cell lineage
IL5; FCER2; HLA-DRB3; CD1D; IL5RA; FCGR1A; ITGA2B; CD1B; MME; CD1C
Amoebiasis
ITGB2; PIK3R3; COL5A2; VCL; GNA11; IL1B2; PRKACG; IL1R2; COL27A1; LAMC2

Protein Function

CD1D has several biochemical functions, for example, beta-2-microglobulin binding, cell adhesion molecule binding, endogenous lipid antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD1D itself. We selected most functions CD1D had, and list some proteins which have the same functions with CD1D. You can find most of the proteins on our site.
Function
Related Protein
Function beta-2-microglobulin binding
Related Protein FCGRT; H2-Q10; CD1E; HFE; CD1B; HLA-E; CD1C; CD1D; HLA-A; CD1d1
Function cell adhesion molecule binding
Related Protein POSTNB; PVRL1; TIGIT; NCR3; PTPRD; CD1d1; PVRL3B; PVRL2; SDCBP; ITGB7
Function endogenous lipid antigen binding
Related Protein CD1E; CD1C; CD1A; CD1B; CD1D; CD1d1; CD1D2
Function exogenous lipid antigen binding
Related Protein CD1D; CD1A; CD1C; CD1D2; CD1d1; CD1E; CD1B
Function histone binding
Related Protein UIMC1; HIST1H4B; USP49; JAK2; H2AFX; MCM2; BAZ2A; UHRF2; ANP32B; ANP32E
Function lipid antigen binding
Related Protein CD1d1; CD1D
Function lipopeptide binding
Related Protein CD1A; CD1C; CD1d1; CD1E; CD1D2; CD1D; CD1B; TLR6
Function receptor activity
Related Protein GUCY1B3; SIGLEC7; CCR6; NLGN3A; TNFRSF9; VPREB1; GFRA2A; NLGN4X; IL18R1; SV2A

CD1D Related Articles

Rosales, C; Tang, DM; et al. CD1d serves as a surface receptor for oxidized cholesterol induction of peroxisome proliferator-activated receptor-gamma. ATHEROSCLEROSIS 239:224-231(2015).
Matsuda, T; Yanase, S; et al. The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation. IMMUNITY & AGEING 12:-(2015).