cenph
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  • Official Full Name
  • centromere protein H
  • Background
  • Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
  • Synonyms
  • CENPH; centromere protein H; NNF1; MIND kinetochore complex component; homolog (S. cerevisiae); PMF1; CENP H; CENP-H; CENPH_HUMAN; ICEN35; Interphase centromere complex protein 35; Kinetochore protein CENP H; NNF1, MIND kinetochore complex component, homolog; OTTHUMP00000123477; OTTHUMP00000221978; OTTHUMP00000221979; kinetochore protein CENP-H
Cat.#:CENPH-1116HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CENPH Protein, GST-Tagged
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Cat.#:CENPH-11095HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPH, His-tagged
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Cat.#:CENPH-26924THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPH, His-tagged
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Cat.#:CENPH-27395THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPH, His-tagged
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Cat.#:CENPH-325HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPH Protein, His-tagged
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Cat.#:CENPH-3644HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CENPH, His-tagged
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Cat.#:Cenph-326MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cenph Protein, His-tagged
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Cat.#:CENPH-3285MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CENPH Protein
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Cat.#:CENPH-6179CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CENPH
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Cat.#:CENPH-6340ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CENPH
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Cat.#:CENPH-7584HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CENPH 293 Cell Lysate
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Involved Pathway

CENPH involved in several pathways and played different roles in them. We selected most pathways CENPH participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
TUBG2; E2F4; LIN52; OFD1; YWHAQB; E2F3; NUDC; PRKDC; CDKN2A; TMEM188
Cell Cycle, Mitotic
DBF4; ZWILCH; CCP110; CENPJ; LMNB1; CDT1; CDKN2B; TUBGCP3; OFD1; TUBGCP2
Chromosome Maintenance
CENPN; CENPK; WRAP53; POT1A; TERF2IP; RBBP4; NPM1; CENPC1; APITD1; PANE1
Deposition of new CENPA-containing nucleosomes at the centromere
RBBP4; MIS18BP1; CENPW; CENPC1; CENPI; CENPO; PANE1; NPM1; SMARCA5; CENPP
M Phase
ARPP19B; NUDC; NDEL1A; CENPO; ZWINT; CENPC1; SETB; CCDC99; CENPH; NCAPG
Mitotic Anaphase
WAPAL; VRK1; NUF2; KNTC1; SKA2; PANE1; ANKLE2; SGOL2; VRK2; RCC2
Mitotic Metaphase and Anaphase
NUDC; NUF2; PANE1; NDEL1A; CENPL; KNTC1; ITGB3BP; CENPN; MLF1IP; ZWINT
Mitotic Prometaphase
ZWINT; AHCTF1; SPC25; RCC2; NSL1; KNTC1; NDEL1; NUDC; SPC24; CLIP1

Protein Function

CENPH has several biochemical functions, for example, kinetochore binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPH itself. We selected most functions CENPH had, and list some proteins which have the same functions with CENPH. You can find most of the proteins on our site.
Function
Related Protein
Function kinetochore binding
Related Protein CCDC99; CLASP1; CLASP1A; SPDL1; CENPH
Function protein binding
Related Protein GLDN; CUL5; C1orf21; IFIH1; ALS2CR11; SH3GL1; CCR5; ITPR1; RASGRP3; PGK1

Interacting Protein

CENPH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPH here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPH.
MTAP; CENPK; PMVK; EMC1; NDC80; q8xb62_eco57; CENPU; CENPQ; Cenpi; CENPO