CHGA Protein, chromogranin A (parathyroid secretory protein 1)

CHGA

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CHGA

Official Full Name chromogranin A (parathyroid secretory protein 1)
Background Pancreastatin belongs to the chromogranin/secretogranin protein family, strongly inhibits glucose induced insulin release from the pancreas. The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
Synonyms CHGA; chromogranin A (parathyroid secretory protein 1); chromogranin-A; SP-I; pituitary secretory protein I; parathyroid secretory protein 1; betagranin (N-terminal fragment of chromogranin A); CGA; CgA; Pancreastatin
    • Species :
    • Human
    • Mouse
    • Pig
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHGA-412H Recombinant Human CHGA Protein, His-tagged E. coli His
    Human CHGA-027H Recombinant Human CHGA Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human CHGA-1360H Recombinant Human CHGA Protein (19-457 aa), His-tagged Yeast His
    Mouse Chga-886M Recombinant Mouse Chga Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CHGA-033H Recombinant Human Chromogranin A (Parathyroid Secretory Protein 1), His-tagged Human His
    Human CHGA-11172H Recombinant Human CHGA, GST-tagged E.coli GST
    Human CHGA-1229H Recombinant Human CHGA Protein, GST-Tagged Wheat Germ GST
    Human CHGA-26904TH Recombinant Human CHGA, His-tagged E.coli His
    Human CHGA-26907TH Recombinant Human CHGA E.coli N/A
    Human CHGA-26908TH Recombinant Human CHGA E.coli N/A
    Human CHGA-403H Recombinant Human Chromogranin A E.coli N/A
    Human CHGA-411H Recombinant Human Chromogranin A, His-tagged E.coli His
    Human CHGA-7540HCL Recombinant Human CHGA 293 Cell Lysate HEK293 N/A
    Mouse CHGA-3390M Recombinant Mouse CHGA Protein Mammalian Cell His
    Mouse Chga-5814M Recombinant Mouse Chga protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque CHGA-843R Recombinant Rhesus monkey CHGA Protein, His-tagged Mammalian Cell His
    Zebrafish CHGA-1569Z Recombinant Zebrafish CHGA Mammalian Cell His
    Pig CHGA-5815P Recombinant Pig CHGA protein, His-tagged E.coli His

    CHGA involved in several pathways and played different roles in them. We selected most pathways CHGA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHGA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    CHGA has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CHGA itself. We selected most functions CHGA had, and list some proteins which have the same functions with CHGA. You can find most of the proteins on our site.

    Function Related Protein

    CHGA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHGA here. Most of them are supplied by our site. Hope this information will be useful for your research of CHGA.

    PFDN1; NEK2; CDC37

    Gottlieb, PA; Delong, T; et al. Chromogranin A is a T cell antigen in human type 1 diabetes. JOURNAL OF AUTOIMMUNITY 50:38-41(2014).
    Nikoopour, E; Cheung, R; et al. Vasostatin-1 antigenic epitope mapping for induction of cellular and humoral immune responses to chromogranin A autoantigen in NOD mice. EUROPEAN JOURNAL OF IMMUNOLOGY 44:1170-1180(2014).

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