cldn18
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  • Official Full Name
  • claudin 18
  • Synonyms
Cat.#:CLDN18-19HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CLDN18 protein, GST-tagged
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Cat.#:CLDN18-20HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CLDN18 protein, GST-tagged
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Cat.#:CLDN18-3529MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CLDN18 Protein
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Cat.#:Cldn18-35MTag:His|SUMO
Source (Host):E.coli cell freeSpecies:Mouse
Product nameRecombinant Mouse Cldn18 protein, His/SUMO-tagged
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Involved Pathway

Cldn18 involved in several pathways and played different roles in them. We selected most pathways Cldn18 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cldn18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
F11R.1; Ntng2; CLDN7A; CD80; CLDN23; CD276; PDCD1; PRPSAP2; ITGB1B.2; F11R
Tight junction
GNAI1; SHROOM4; MPP5A; PRKCQ; RAB3B; MYL12.1; RHOA; SHROOM1; ACTB; MYH6
Leukocyte transendothelial migration
PTK2B; CXCL12; PLCG1; ACTG1; ITGAL; CXCR4; AASS; MYL5; CLDN2; PIK3CG
Hepatitis C
TBK1; OAS2; MAPK12; IFNA1; PPP2R2D; STAT3; CLDN15; OAS1B; NFKBIA; CLDN4

Protein Function

Cldn18 has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cldn18 itself. We selected most functions Cldn18 had, and list some proteins which have the same functions with Cldn18. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein YY1A; TXLNA; SORL1; PIK3IP1; DLG4; ZFC3H1; DZIP1; HIST1H1A; BCKDHB; RPS27A
Function structural molecule activity
Related Protein SPRR4; COL15A1B; LCE1B; RLN3B; CLDNJ; KRT82; LMNTD1; FLG; SNTB2; PGM5

Interacting Protein

Cldn18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cldn18 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cldn18.
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Cldn18 Related Articles

Micke, P; Mattsson, JSM; et al. Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer. INTERNATIONAL JOURNAL OF CANCER 135:2206-2214(2014).
Woll, S; Schlitter, AM; et al. Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms. INTERNATIONAL JOURNAL OF CANCER 134:731-739(2014).