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Cldn18

  • Official Full Name

    claudin 18

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Cynomolgus monkey
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Mouse
  • Mus musculus (Mouse)
  • Baculovirus-Insect cells
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GFP
  • GST
  • His (Fc)
  • Avi
  • Twin
  • Strep
  • His|SUMO
  • mCherry
  • N/A
  • N
  • Twin strep
  • Flag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLDN18-835H Active Recombinant Human CLDN18 protein, His-Twin-Strep-tagged(Nanodisc) Insect Cell His-Twin-Strep Met 1 - Ala 200
Human CLDN18-857H Active Recombinant Human CLDN18 protein HEK293 Met1-Val261
Human CLDN18-395H Active Fluorescent Recombinant Human ADORA2A Full Length Transmembrane protein(VLPs) HEK293 N/A
Human CLDN18-396H Active Recombinant Human ADORA2A Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CLDN18-059H Active Recombinant Human CLDN18 protein HEK293 N/A Met 1 - Val 261
Human CLDN18-3152H Active Recombinant Human CLDN18 Full Length Transmembrane protein(VLPs) HEK293 N/A
Human CLDN18-2349H Active Recombinant Human CLDN18 Full Length protein(VLPs) HEK293 N/A Met 1- Val 261
Human CLDN18-2350H Active Recombinant Fluorescent Human CLDN18 Full Length protein(VLPs) HEK293 N/A Met 1- Val 261
Human CLDN18-3231H Active Fluorescent Recombinant Human CLDN18 Full Length Transmembrane protein(VLPs) HEK293 N/A Met 1 - Val 261
Human CLDN18-392H Active Recombinant Human CLDN18 Full Length Transmembrane protein(VLPs) HEK293 N/A Met 1 - Val 261
Human CLDN18-19H Recombinant Human CLDN18 protein, GST-tagged Wheat Germ GST 1 a.a. - 261 a.a.
Human CLDN18-20H Recombinant Human CLDN18 protein, GST-tagged Wheat Germ GST 196 a.a. - 261 a.a.
Human CLDN18-0105H Recombinant Human CLDN18 Protein (Met1-Val261), C-His-tagged Baculovirus-Insect cells C-His Met1-Val261
Human CLDN18-393H Active Recombinant Human CLDN18 Full Length Transmembrane protein(VLPs), Biotinylated HEK293 N/A Met 1 - Val 261
Human CLDN18-057H Recombinant Human CLDN18 protein, His&Twin-Strep-tagged(VLPs) Insect Cell His&Twin-Strep Met 1 - Ala 200
Human CLDN18-856H Recombinant Human CLDN18 protein, His-tagged E.coli His Met27-Arg80 & Val136-Ala 184
Human CLDN18-794H Recombinant Human CLDN18 Protein, His-tagged E.coli N-His Cys196-Val261
Human CLDN18-0294H Recombinant Human CLDN18 Full Length Transmembrane protein, mCherry-tagged HEK293 mCherry 1-261aa
Human CLDN18-0106H Recombinant Human CLDN18 Protein (Met1-Val262), C-His-tagged Baculovirus-Insect cells C-His Met1-Val262
Human CLDN18-056H Recombinant Human CLDN18 protein, GFP-tagged(VLPs) HEK293 GFP Met 1 - Val 261
Human CLDN18-692HF Recombinant Full Length Human CLDN18 Protein, GST-tagged In Vitro Cell Free System GST 261 amino acids
Human CLDN18-2348H Active Recombinant Human CLDN18 Full Length protein(VLPs) HEK293 N/A Met 1- Val 261
Human CLDN18-382H Active Recombinant Human CLDN18 Full Length Transmembrane protein(VLPs) HEK293 N/A Met1-Val261
Human CLDN18-383H Active Fluorescent Recombinant Human CLDN18 Full Length Transmembrane protein(VLPs) HEK293 N/A Met1-Val261
Human CLDN18-3772H Recombinant Human CLDN18 Protein (Met1-Val261), C-His tagged Insect Cells C-His Met1-Val261
Human CLDN18-058H Recombinant Human CLDN18 protein, His&Avi-tagged, Biotinylated(VLPs) Insect Cell His&Avi Met 1 - Ala 200
Human CLDN18-8113H Active Recombinant Human CLDN18 protein, Twin strep-Flag-tagged HEK293 Twin strep-Flag Met1-Ala200
Mouse CLDN18-835M Active Recombinant Mouse CLDN18 protein, His-Twin-Strep-tagged(Detergent) Insect Cell His-Twin-Strep Met 1 - Thr 203
Mouse Cldn18-35M Recombinant Mouse Cldn18 protein, His/SUMO-tagged E.coli His/SUMO 1-264 aa
Mouse CLDN18-3529M Recombinant Mouse CLDN18 Protein Mammalian Cell His
Mouse CLDN18-1730M Recombinant Mouse CLDN18 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CLDN18-1730M-B Recombinant Mouse CLDN18 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cldn18-019M Active Recombinant Mouse Cldn18 Full Length Transmembrane protein, His-tagged HEK293 His 1-264aa
Mouse Cldn18-36M Active Recombinant Mouse CLDN18 protein, 6xHis-tagged(VLPs) HEK293 His 1-264aa
Bos taurus (Bovine) RFL6940BF Recombinant Full Length Bovine Claudin-18(Cldn18) Protein, His-Tagged E.coli expression system His Full Length (1-261)
Cynomolgus monkey CLDN18-1021C Active Recombinant Cynomolgus monkey CLDN18 Full Length Transmembrane protein, His-tagged HEK293 His 1-261aa
Homo sapiens (Human) RFL6794HF Recombinant Full Length Human Claudin-18(Cldn18) Protein, His-Tagged E.coli expression system His Full Length (1-261)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL11404MF Recombinant Full Length Macaca Fascicularis Claudin(Cldn18)-Vlps (Active) Protein, His-Tagged E.coli expression system His Full Length (1-261aa)
Mus musculus (Mouse) RFL14670MF Recombinant Full Length Mouse Claudin-18(Cldn18) Protein, His-Tagged E.coli expression system His Full Length (1-264)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Cldn18 Related Articles
  • Cldn18 Related Research Area

Cldn18 involved in several pathways and played different roles in them. We selected most pathways Cldn18 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cldn18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)BLB1;OCLNA;CNTNAP1;BF1;ALCAMA;HLA-DQA2;ITGB7;MAG;PTPRM
Tight junctionPRKCA;PPP2R1A;YBX3;PRKCG;VMHC;CLDN11A;MYH4;GNAI1;CLDN17
Leukocyte transendothelial migrationCDC42;MSN;BCAR1;RAP1B;PRKCB;JAM3;NOX3;ACTN1;CLDN5
Hepatitis CIFNA4;NR1H3;RNASEL;CLDN4;PIK3CB;CLDN22;EIF2AK2;SCARB1;CLDN6

Cldn18 has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cldn18 itself. We selected most functions Cldn18 had, and list some proteins which have the same functions with Cldn18. You can find most of the proteins on our site.

Function Related Protein
protein bindingFDX1L;DACT2;NCAPD2;EREG;FES;CSNK1A1;IL12B;CDIPT;VAC14
structural molecule activityKRT77;MAP7;CKI;DSP;CLDN15;KRT8;DESMB;SEPT7;PSMD13

Cldn18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cldn18 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cldn18.

Ywhae

Micke, P; Mattsson, JSM; et al. Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer. INTERNATIONAL JOURNAL OF CANCER 135:2206-2214(2014).
Woll, S; Schlitter, AM; et al. Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms. INTERNATIONAL JOURNAL OF CANCER 134:731-739(2014).
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