cma1
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  • Official Full Name
  • chymase 1, mast cell
  • Background
  • Monocyte chemotactic protein 5 (MCP-5);, also known as CCL 12, is a novel and potent monocyte active chemokine that is involved in allergic inflammation and the host response to pathogens.1 It is also a potent chemoattractant for peripheral blood monocyte
  • Synonyms
  • CMA1; chymase 1, mast cell; chymase; alpha-chymase; mast cell chymase 1; mast cell protease 5; mast cell protease I; Mcp5; Mcp-5; Mcpt5; MMCP-5
Cat.#:CMA1-1364DTag:His
Source (Host):YeastSpecies:Dog
Product nameRecombinant Dog CMA1 Protein (22-249 aa), His-tagged
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Cat.#:CMA1-2111CTag:His-SUMO
Source (Host):E. coliSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus Monkey CMA1 Protein (22-247 aa), His-SUMO-tagged
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Cat.#:CMA1-412DTag:His-SUMO
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog CMA1 Protein (22-249 aa), His-SUMO-tagged
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Cat.#:CMA1-1530HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CMA1 Protein, GST-tagged
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Cat.#:Cma1-211MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cma1 Protein, His-tagged
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Cat.#:Cma1-508MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cma1 Protein, His/GST-tagged
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Cat.#:Cma1-509RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cma1 Protein, His-tagged
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Cat.#:CMA1-11359HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CMA1, GST-tagged
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Cat.#:CMA1-1776HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CMA1 protein, His-tagged
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Cat.#:CMA1-2503HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CMA1, His tagged
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Cat.#:CMA1-25HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human CMA1 protein, His-tagged
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Cat.#:CMA1-722HTag:N/A
Source (Host):YeastSpecies:Human
Product nameRecombinant Human Chymase 1, Mast Cell
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Cat.#:Cma1-101MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Murine Chymase 1, Mast cell
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Cat.#:CMA1-1477RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CMA1 Protein
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Cat.#:CMA1-413CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CMA1 Protein, His-tagged
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Cat.#:CMA1-924RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CMA1 Protein, His-tagged
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Cat.#:CMA1-35HTag:
Source (Host):Human skinSpecies:Human
Product nameNative Human CMA1 protein
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Cat.#:CMA1-493HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CMA1 cell lysate
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Involved Pathway

Cma1 involved in several pathways and played different roles in them. We selected most pathways Cma1 participated on our site, such as ACE Inhibitor Pathway, Activation of Matrix Metalloproteinases, Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cma1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ACE Inhibitor Pathway
AGT; CMA1; AGTR1; AGTR2; ACE; CYP11B2; CTSG; ATP6AP2
Activation of Matrix Metalloproteinases
MMP17; TIMP2A; MGC174152; MMP24; CTSG; FURINB; LOC100686744; MMP10; MGC174155; CMA1
Degradation of the extracellular matrix
COL17A1; CMA1; FAM49BA; ADAM8A; CTSS; CTSL2; CTSK; MMP8; ACAN; ELANE
Extracellular matrix organization
MMP15; LOXL1; COL25A1; PCOLCEA; COL5A1; ADAMTS2; BMP1A; MFAP4; COL4A4; SERPINH1B
Metabolism of Angiotensinogen to Angiotensins
CPB1; CPB2; ATP6AP2; CPA3; ACE; GZMH; CTSG; CMA1
Metabolism of proteins
ODAM; PMPCB; SLC30A8; ZNF408; FKBP9; NAPAB; FURINB; C19orf10; ARSF; SCFD1
Peptide hormone metabolism
GPR119; GRP; CPE; GZMH; CPA3; CPB1; CPN1; RAB27A; PCSK1; CPB2
Renin-angiotensin system
THOP1; REN; MAS1; KLK1B26; ENPEP; MRGPRD; NLN; MME; REN2; LNPEP

Protein Function

Cma1 has several biochemical functions, for example, peptide binding, serine-type endopeptidase activity, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cma1 itself. We selected most functions Cma1 had, and list some proteins which have the same functions with Cma1. You can find most of the proteins on our site.
Function
Related Protein
Function peptide binding
Related Protein NPFFR2; CMA1; CSNK1D; THOP1; CRIP1; FURIN; PPYR1; GNRHR2; ERCC3; ANPEPA
Function serine-type endopeptidase activity
Related Protein KLK12; PREP; PCSK2; KLK1B3; TPP1; KLK1B4; PCSK1; ELA2L; CTRC; KLK10
Function serine-type peptidase activity
Related Protein MCPT9; CFD; DPP4; KEX2; SEC11C; TPSAB1; PRSS16; TMPRSS13A; SLC38A8; DPP8