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Cma1

  • Official Full Name

    chymase 1, mast cell

  • Overview

    Monocyte chemotactic protein 5 (MCP-5);, also known as CCL 12, is a novel and potent monocyte active chemokine that is involved in allergic inflammation and the host response to pathogens.1 It is also a potent chemoattractant for peripheral blood monocyte
  • Synonyms

    CMA1; chymase 1, mast cell; chymase; alpha-chymase; mast cell chymase 1; mast cell protease 5; mast cell protease I; Mcp5; Mcp-5; Mcpt5; MMCP-5;

  • Recombinant Proteins
  • Native Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Dog
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Human Skin
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • P.pastoris
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CMA1-25H Active Recombinant Human CMA1 protein, His-tagged Mammalian cells His Met1-Asn247
Human CMA1-722H Active Recombinant Human Chymase 1, Mast Cell P.pastoris N/A
Human CMA1-35H Active Native Human CMA1 protein Human Skin N/A
Human CMA1-1530H Recombinant Human CMA1 Protein, GST-tagged Wheat Germ GST
Human CMA1-2503H Recombinant Human CMA1 protein, His-tagged Insect Cells His Met1-Asn247
Human CMA1-11359H Recombinant Human CMA1, GST-tagged E.coli GST 1-247a.a.
Human CMA1-493HCL Recombinant Human CMA1 cell lysate Insect Cell N/A
Human CMA1-1898HF Recombinant Full Length Human CMA1 Protein, GST-tagged In Vitro Cell Free System GST 247 amino acids
Human CMA1-2694H-B Recombinant Human CMA1 Protein Pre-coupled Magnetic Beads HEK293
Human CMA1-2694H Recombinant Human CMA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CMA1-1748H Recombinant Human CMA1 Protein (Ile22-Asn247), His tagged E.coli His Ile22-Asn247
Human CMA1-1776H Recombinant Human CMA1 protein, His-tagged E.coli His Ile22~Asn247
Mouse Cma1-101M Recombinant Murine Chymase 1, Mast cell E.coli N/A
Mouse Cma1-211M Recombinant Mouse Cma1 Protein, His-tagged E.coli His Ser28~Gly104
Mouse Cma1-2708M Recombinant Mouse Cma1 protein, His-tagged E.coli His 22-246aa
Mouse Cma1-508M Recombinant Mouse Cma1 Protein, His/GST-tagged E.coli His/GST Leu9~Asn247
Rat CMA1-1477R Recombinant Rat CMA1 Protein Mammalian Cell His
Rat CMA1-1135R-B Recombinant Rat CMA1 Protein Pre-coupled Magnetic Beads HEK293
Rat CMA1-1135R Recombinant Rat CMA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cma1-509R Recombinant Rat Cma1 Protein, His-tagged E.coli His Ile22~Asn247
Dog CMA1-412D Recombinant Dog CMA1 Protein (22-249 aa), His-SUMO-tagged E.coli His/SUMO 22-249 aa
Dog CMA1-1364D Recombinant Dog CMA1 Protein (22-249 aa), His-tagged Yeast His 22-249 aa
Cynomolgus Monkey CMA1-413C Recombinant Cynomolgus CMA1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CMA1-2111C Recombinant Cynomolgus Monkey CMA1 Protein (22-247 aa), His-SUMO-tagged E.coli His/SUMO 22-247 aa
Cynomolgus Monkey CMA1-161C-B Recombinant Cynomolgus Monkey CMA1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey CMA1-161C Recombinant Cynomolgus Monkey CMA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CMA1-924R Recombinant Rhesus monkey CMA1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CMA1-749R-B Recombinant Rhesus Macaque CMA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CMA1-749R Recombinant Rhesus Macaque CMA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Cma1 Related Research Area

Cma1 involved in several pathways and played different roles in them. We selected most pathways Cma1 participated on our site, such as ACE Inhibitor Pathway, Activation of Matrix Metalloproteinases, Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cma1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ACE Inhibitor PathwayAGTR2;CMA1;CYP11B2;ACE;ATP6AP2;CTSG;AGT;AGTR1
Activation of Matrix MetalloproteinasesCTSLL;LOC100686744;MGC174155;TIMP2A;MMP11;TIMP2B;ELANE;MMP15;CTSK
Degradation of the extracellular matrixCAPNS1;ADAMTS5;ADAMTS1;BMP1B;LOC100686744;CTRB1;COL15A1B;COL9A1;MGC174857
Extracellular matrix organizationPCOLCEA;PCOLCE;LEPREL2;ADAMTS5;FAM49BA;MFAP4;MFAP1B;COL19A1;TLL1
Metabolism of Angiotensinogen to AngiotensinsACE;CTSG;GZMH;ATP6AP2;CPB1;CPA3;CPB2;CMA1
Metabolism of proteinsCGB5;ST3GAL3A;MAN1A2;CPA3;RNF2;B3GNT6;TOMM7;SPCS3;C8orf84
Peptide hormone metabolismMBOAT4;CPB1;ATP6AP2;PCSK1;SLC30A6;CPB2;GZMH;EXOC8;INHBAA
Renin-angiotensin systemTHOP1;KLK2;KLK1B8;KLK1B22;AGTR1B;KLK1B1;AGTR1A;CPA3;KLK1B3

Cma1 has several biochemical functions, for example, peptide binding, serine-type endopeptidase activity, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cma1 itself. We selected most functions Cma1 had, and list some proteins which have the same functions with Cma1. You can find most of the proteins on our site.

Function Related Protein
peptide bindingCTSB;CCKAR;RPS6KB2;FURIN;THOP1;GNRHR;ANPEP;LNPEP;BDKRB1
serine-type endopeptidase activityHTRA3;HTRA1A;Prss32;MCPT1;MST1;KLK1B5;PIK3IP1;TMPRSS11B;FURINA
serine-type peptidase activitySEC11A;HGFA;PRSS8;Acr;PRSS12;Gzmg;C1rb;GZMK;PRSS30

Cma1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cma1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cma1.

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