cxcr5
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  • Official Full Name
  • chemokine (C-X-C motif) receptor 5
  • Background
  • This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitts lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • Synonyms
  • CXCR5; chemokine (C-X-C motif) receptor 5; BLR1; CD185; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5);
Cat.#:CXCR5-9162HTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CXCR5
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Cat.#:CXCR5-9163HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CXCR5, GST-tagged
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Cat.#:CXCR5-4111MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CXCR5 Protein
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Cat.#:CXCR5-1695RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CXCR5 Protein
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Cat.#:CXCR5-2601CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CXCR5
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Cat.#:CXCR5-426HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CXCR5 cell lysate
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Cat.#:Kit-1060Tag:
Source (Host):Species:
Product nameHIV-1 Protease Assay Kit
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Cat.#:Kit-1200Tag:
Source (Host):Species:
Product nameCXCR5 (BLR1) CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-1201Tag:
Source (Host):Species:
Product nameCHO-K1 CXCR5 Bioassay Kit
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Cat.#:Kit-1202Tag:
Source (Host):Species:
Product namecAMP CXCR5 (BLR1) CHO-K1 GPCR Assay Kit
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Involved Pathway

CXCR5 involved in several pathways and played different roles in them. We selected most pathways CXCR5 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCR5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
IL23R; CXCL11; IFNA4; IL25; BMPR2B; AMH; Ccl21c; IL26; IL1R1; IFNA2
Chemokine signaling pathway
LOC100033925; GNG4; GRK4; NFKB1; CCL21B; ARRB1; GSK3A; GNG3; GNG11; Cxcl15

Protein Function

CXCR5 has several biochemical functions, for example, C-X-C chemokine receptor activity, G-protein coupled receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCR5 itself. We selected most functions CXCR5 had, and list some proteins which have the same functions with CXCR5. You can find most of the proteins on our site.
Function
Related Protein
Function C-X-C chemokine receptor activity
Related Protein CXCR6; CCR9A; CXCR4; CXCR2; CCBP2; CXCR4B; CXCR5; CXCR7; CXCR3; CXCR3.1
Function G-protein coupled receptor activity
Related Protein CXCR4A; OR10A4; GPR18; FZD2; V1RA8; OR4F29; PARAPINOPSINB; TAAR7B; TAAR14J; TAS1R2.2
Function protein binding
Related Protein MORN2; MYO7A; RTP4; THOC5; MAPKAPK2; PTPN13; OSBP; MYO1C; DIS3L; DEPDC1

Interacting Protein

CXCR5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCR5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCR5.
GNAI2; GNAO1; GNB3; GNAQ; CXCR4; GNA13

CXCR5 Related Articles

Klimatcheva, E; Pandina, T; et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC IMMUNOLOGY 16:-(2015).
Spaan, M; Kreefft, K; et al. CD4(+)CXCR5(+) T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses. JOURNAL OF HEPATOLOGY 62:303-310(2015).

CXCR5 Related Gene Family

Chemokines Cytokines