|Official Full Name||dynamin 1|
|Background||This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3 region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.|
|Synonyms||DNM1; dynamin 1; DNM; dynamin-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
DNM1 involved in several pathways and played different roles in them. We selected most pathways DNM1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||ASB8; KIFAP3; CTSLL; KLHL21; CTSK; NCR3LG1; UBE2V1; UBE2F; HECTD3; DCTN3|
|Axon guidance||ACTR3; COL9A1A; NRP1; ABL1; ACTR2; AP2A2; SEMA6B; SIAH2; ARPC2; SPTB|
|Bacterial invasion of epithelial cells||CLTA; VCL; ITGB1; SHC3; CDH1; PXN; ITGA5; RHOG; FN1; PIK3CB|
|CXCR3-mediated signaling events||MAPKAP1; DNM1; CXCL13|
|CXCR4-mediated signaling events||PAG1; MAPKAP1; ADRBK1; CSK; CRK; GNA13; ARR3; DNM1; CFL1; BLK|
|Developmental Biology||COL9A3; FGF20A; SCN3A; LGI2; ANK2B; CACNG8A; DCC; COL4A4; ITSN1; DUSP2|
|EGFR1 Signaling Pathway||RGS5B; ABI1B; TNK2; RBB4L; REPS2; CEACAM1; RGS16; EPPK1; CEBPB; TNIP1|
|EPH-Ephrin signaling||ARPC1A; SHB; EFNB3; AP2S1; EFNA3; AP2M1; KALRN; EPHA2; EPHB4B; KALRNB|
DNM1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by DNM1 itself. We selected most functions DNM1 had, and list some proteins which have the same functions with DNM1. You can find most of the proteins on our site.
|GTP binding||SCG5; REM1; HRASA; RAB35; RNGTT; TUBA1A; RHOB; RND2; ATL1; TUBA3D|
|GTPase activity||DIRAS3; RAB44; GIMAP7; DNM2B; TUBA8L4; RAC2; TUBA3E; RAB18; GNAV1; GNAS|
|identical protein binding||LYZ; MICALL1; KHDRBS1; ALCAMB; KCTD17; PFKM; GAPDH; HOOK1; CLPP; PRNP|
|poly(A) RNA binding||OTUD4; RBM4B; ILF3; THRAP3; HSP90AB1; GOT2; MBNL3; RPS9; DUSP11; CNOT1|
|protein binding||C19orf44; ACBD3; GTF2H4; BAIAP2L1; ADAM10; SKI; CD97; CAMK2D; B9D2; REST|
|protein dimerization activity||MESP1; HES4; HIF1AB; POLR2J2; EBF4; NCF4; DAO; NEUROD6A; EBF3A; STAT5B|
|protein kinase binding||SYN1; GYS1; CD4; CNPPD1; APC; PTPN1; TNIP2; HSP90AB1; TMEM173; RAB8A|
DNM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNM1.
GRB2; SNX9; AMPH