DPYSL2

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DPYSL2

Official Full Name dihydropyrimidinase-like 2
Background Collapsin Response Mediator Protein-2 (CRMP-2) is expressed at high levels in the developing nervous system and plays a critical role in axonal outgrowth by specifying axon/dendrite fate and establishing neuronal polarity. CRMP-2 enhances axon elongation
Synonyms DPYSL2; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; CRMP2; DHPRP2; DRP 2; DRP2; unc-33-like phosphoprotein 2; collapsin response mediator protein hCRMP-2; N2A3; DRP-2; ULIP2; CRMP-2; ULIP-2
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Dpysl2-2651M Recombinant Mouse Dpysl2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human DPYSL2-6183H Recombinant Human DPYSL2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DPYSL2-101H Recombinant Human DPYSL2, GST-tagged Wheat Germ GST
    Human DPYSL2-102H Recombinant Human DPYSL2, GST-tagged Wheat Germ GST
    Human DPYSL2-1193H Recombinant Human DPYSL2 Protein, His-tagged Yeast His
    Human DPYSL2-2539H Recombinant Human DPYSL2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse DPYSL2-4812M Recombinant Mouse DPYSL2 Protein Mammalian Cell His
    Rat DPYSL2-1949R Recombinant Rat DPYSL2 Protein Mammalian Cell His
    Chicken DPYSL2-6064C Recombinant Chicken DPYSL2 Mammalian Cell His

    DPYSL2 involved in several pathways and played different roles in them. We selected most pathways DPYSL2 participated on our site, such as Axon guidance, BDNF signaling pathway, CRMPs in Sema3A signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPYSL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance DUSP2; HFE2; GNAI1; EPHA8; EFNB1; GFRA4; SEMA3D; GDNF; DPYSL4; SPNA1
    BDNF signaling pathway EIF4EBP1; SIRPA; GRIP1; IGF2BP1; EIF4E; KCNN2; GNB2L1; CSNK2A1P; CDKL5; FRS2
    CRMPs in Sema3A signaling SEMA3A; DPYSL4; CDK5; DPYSL2; SEMA3AA; NRP1A; DPYSL5A; CDK5R1B; DPYSL2B; CRMP1
    Developmental Biology GPC1A; MED20; MED19; COL6A1; DPYSL5A; RHOAE; COL9A1; DUSP10; POU5F3; SCN9A
    L1CAM interactions NRP2; DCX; DLG3; CNTN1; SCN2A; CNTN6; SCN4A; KIF4; RANBP9; NADL1.1
    Recycling pathway of L1 DPYSL2; DPYSL2B; EZRA; NADL1.1
    Regulation of Microtubule Cytoskeleton CFL2; MARK2; TESK2; DPYSL2; MARK1; TPPP; MAP1B
    Semaphorin interactions CRMP1; DPYSL5B; DPYSL4; CDK5R1B; SEMA3A; RND1L; SEMA3AB; SEMA3AA; NRP1A; PLXND1

    DPYSL2 has several biochemical functions, for example, dihydropyrimidinase activity, microtubule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPYSL2 itself. We selected most functions DPYSL2 had, and list some proteins which have the same functions with DPYSL2. You can find most of the proteins on our site.

    Function Related Protein
    dihydropyrimidinase activity DPYSL2; DPYS
    microtubule binding SPAST; MAP2; KCNH2A; MTUS2; KIAA1128; GOLSYN; CCDC87; FNTA; GABARAP; CDK5RAP2
    protein binding CLSTN2; COLQ; BRCC3; CYTIP; NDE1; BCL7B; LOXL2; HOOK1; PAIP2; VBP1
    protein kinase binding CCNL1; MLKL; CHEK2; SHC3; SOCS1; RELA; FGR; GSK3B; MAP3K5; VRK1

    DPYSL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPYSL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPYSL2.

    DPYSL3; DPYSL3; DPYSL5; GORASP2; MICALL1; GRK1; DPYSL4

    Tan, F; Wahdan-Alaswad, R; et al. Dihydropyrimidinase-like protein 3 expression is negatively regulated by MYCN and associated with clinical outcome in neuroblastoma. CANCER SCIENCE 104:1586-1592(2013).

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