efna3
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  • Official Full Name
  • ephrin-A3
  • Background
  • This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin.
  • Synonyms
  • EFNA3; ephrin-A3; EPLG3; Ehk1 L; LERK3; EFL-2; LERK-3; EHK1 ligand; ligand of eph-related kinase 3; eph-related receptor tyrosine kinase ligand 3; EFL2; Ehk1-L
Cat.#:EFNA3-3099HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EFNA3 Protein, GST-tagged
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Cat.#:EFNA3-155HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA3, His-tagged
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Cat.#:EFNA3-1609HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Ephrin-A3
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Cat.#:EFNA3-160HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA3, Fc-tagged
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Cat.#:EFNA3-177HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human EFNA3, Fc Chimera
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Cat.#:EFNA3-178HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human EFNA3, Fc Chimera, Biotinylated
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Cat.#:EFNA3-196HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA3 Protein, Fc-tagged
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Cat.#:EFNA3-28626THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human EFNA3
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Cat.#:EFNA3-3151HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA3, His tagged
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Cat.#:EFNA3-3812HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Ephrin-A3
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Cat.#:EFNA3-579HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ephrin-A3, His-tagged
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Cat.#:EFNA3-699HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA3, None tagged
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Cat.#:EFNA3-77HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA3, Fc-His tagged
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Cat.#:Efna3-4055MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Efna3, His tagged
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Cat.#:Efna3-630MTag:Fc
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Efna3 Protein, Fc Chimera
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Cat.#:EFNA3-1392RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey EFNA3 Protein, His-tagged
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Cat.#:EFNA3-2437HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human EFNA3 cell lysate
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Cat.#:EFNA3-2160MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse EFNA3 cell lysate
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Involved Pathway

EFNA3 involved in several pathways and played different roles in them. We selected most pathways EFNA3 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EFNA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
NCK1; PAK1; DPYSL4; NTNG1; NRP1A; ITSN1; ABLIM3; COL9A1B; NTN1; EPHA4A
Developmental Biology
SPTBN2; JAK1; KIF4A; HIF3A; DPYSL3; COL9A1B; SEMA3AA; NTN1B; INSM1B; ARPC3
EPH-Ephrin signaling
ACTR2; EFNA1A; ARPC2; EFNA3B; AP2B1; EFNB3; EPHB4B; ACTR2B; KALRNB; EPHA2
EPH-ephrin mediated repulsion of cells
EPHB4B; EFNB3B; AP2B1; CLTB; EPHB4A; EFNA2A; EFNB1; EFNA3; EPHA2A; EFNA3B
EPHA forward signaling
EFNA1; EFNA3; BLK; CRKL; EPHA2; EFNA2; EFNA5; ARHGEF15
EPHA-mediated growth cone collapse
MYL12B; EFNA2A; KDR; EPHA2; EFNA1B; EPHA4A; EFNA3B; EPHA10; EFNA2; EPHA2A
MicroRNAs in cancer
TNXB; RECK; ROCK1; CCNE1; PIM1; RAF1; ZEB2; SLC45A3; BAK1; MCL1
PI3K-Akt signaling pathway
CSH1; COMP; CSF1R; EFNA2; CDC37; CSF3; CSH2; LAMC3; CHAD; SGK2

Protein Function

EFNA3 has several biochemical functions, for example, ephrin receptor binding, protein binding, transmembrane-ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EFNA3 itself. We selected most functions EFNA3 had, and list some proteins which have the same functions with EFNA3. You can find most of the proteins on our site.
Function
Related Protein
Function ephrin receptor binding
Related Protein EFNB2B; SHC1; EPHA7; CDK5; FYN; SRC; EFNB1; EFNA5B; EPHA4; PTPN1
Function protein binding
Related Protein COP1; UBE3C; CCDC116; ROPN1B; CEBPA; COPE; GCKR; SEPHS1; STOML2; MIEN1
Function transmembrane-ephrin receptor activity
Related Protein EPHB1; EFNB3; EFNA4; EPHA4; EPHA10; EPHA1; EFNA3; EPHA5; EPHB2

Interacting Protein

EFNA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EFNA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EFNA3.
MEOX2; NOTCH2NL; PRSS23