f11
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  • Official Full Name
  • coagulation factor XI
  • Background
  • Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene.
  • Synonyms
  • coagulation factor XI; F11; FXI; MGC141891; PTA; OTTHUMP00000197033; plasma thromboplastin antecedent
Cat.#:F11-3602HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human F11 Protein, GST-tagged
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Cat.#:F11-957HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human F11 Protein, MYC/DDK-tagged
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Cat.#:F11-1861HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human F11 protein, His & T7-tagged
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Cat.#:F11-290HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human F11, His tagged
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Cat.#:F11-5404MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse F11 Protein
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Cat.#:F11-766MTag:His
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse F11 Protein, His-tagged
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Cat.#:F11-1862RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat F11 protein, His & GST-tagged
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Cat.#:F11-2466HTag:N/A
Source (Host):Human plasmaSpecies:Human
Product nameNative Human Coagulation Factor XI
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Cat.#:F11-2681HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human F11 cell lysate
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Cat.#:F11-178HTag:
Source (Host):Species:Human
Product nameHuman Blood Coagulation Factor XI Reference standard
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Cat.#:F11-42HTag:
Source (Host):Species:Human
Product nameFactor XI Reference standard
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Involved Pathway

F11 involved in several pathways and played different roles in them. We selected most pathways F11 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with F11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Complement and coagulation cascades
C4BPB; C4A; C1RA; F10; SERPINA1A; BDKRB1; THBD; C5AR1; KLKB1; GM5077

Protein Function

F11 has several biochemical functions, for example, heparin binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by F11 itself. We selected most functions F11 had, and list some proteins which have the same functions with F11. You can find most of the proteins on our site.
Function
Related Protein
Function heparin binding
Related Protein VEGFAA; SLIT2; LIPG; CCL5; FGF1A; SERPINA5; SLIT1A; GM4980; PTPRFB; APP
Function protein binding
Related Protein DDX23; TDRD7; ATP2C2; SLC2A1; NIPAL1; FKBP4; DFFA; FBN2; HUWE1; WT1
Function serine-type endopeptidase activity
Related Protein TMPRSS4A; TMPRSS4; TMPRSS11G; TPP1; GZME; ELANE; PARLA; KLK9; ELA2L; MMP8

Interacting Protein

F11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with F11 here. Most of them are supplied by our site. Hope this information will be useful for your research of F11.
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F11 Related Articles

Gonzalez-Burgos, E; Fernandez-Moriano, C; et al. Potential Neuroprotective Activity of Ginseng in Parkinson's Disease: A Review. JOURNAL OF NEUROIMMUNE PHARMACOLOGY 10:14-29(2015).
Bruzelius, M; Bottai, M; et al. Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13:219-227(2015).

F11 Related Gene Family

TGF Kinesins (KIF) Cytokines