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GABARAP

  • Official Full Name

    GABA(A) receptor-associated protein

  • Overview

    Gamma-aminobutyric acid A receptors (GABA(A) receptors) are ligand-gated chloride channels that mediate inhibitory;neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its;N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This;protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
  • Synonyms

    GABARAP; GABA(A) receptor-associated protein; gamma-aminobutyric acid receptor-associated protein; ATG8A; MM46; GABARAP-a; FLJ25768; MGC120154; MGC120155;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|MBP
  • N/A
  • N
  • C
  • Fc
  • MBP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GABARAP-580H Active Recombinant Human GABARAP Protein, His-tagged Protein, Fluorescein E.coli His
Human GABARAP-582H Active Recombinant Human GABARAP Protein, His-tagged Protein, Rhodamine E.coli His
Human GABARAP-581H Active Recombinant Human GABARAP Protein, Agarose E.coli N/A
Human GABARAP-1010H Recombinant Human GABA(A) Receptor-associated Protein E.coli N/A
Human GABARAP-4365H Recombinant Human GABA(A) receptor-associated protein, His-tagged Human His
Human GABARAP-578H Recombinant Human GABARAP Protein, His-tagged E.coli His
Human GABARAP-579H Recombinant Human GABARAP Protein, His-tagged Protein, Biotinylated E.coli His
Human GABARAP-703H Recombinant Human GABARAP Protein, His&MBP-tagged E.coli His/MBP
Human GABARAP-13085H Recombinant Human GABARAP, GST-tagged E.coli GST 1-117a.a.
Human GABARAP-288H Recombinant Human GABARAP protein(Met1-Leu117), His&MBP-tagged E. coli N-His&MBP Met1-Leu117
Human GABARAP-26082TH Recombinant Human GABARAP, His-tagged E.coli His
Human GABARAP-4622H Recombinant Human GABARAP Protein, GST-tagged Wheat Germ GST
Human GABARAP-937H Recombinant Human GABARAP Protein, GST-tagged E.coli GST
Human GABARAP-5148HF Recombinant Full Length Human GABARAP Protein, GST-tagged In Vitro Cell Free System GST 117 amino acids
Human GABARAP-939H Recombinant Human GABARAP Protein, His-tagged E.coli His
Human GABARAP-5224H Recombinant Human GABARAP protein, GST-tagged E.coli GST 2-117aa
Human GABARAP-3465H Recombinant Human GABARAP Protein (Met1-Gln116), N-His and C-Fc tagged E.coli N-His and C-Fc Met1-Gln116
Mouse GABARAP-6138M Recombinant Mouse GABARAP Protein Mammalian Cell His
Mouse GABARAP-3421M Recombinant Mouse GABARAP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GABARAP-3421M-B Recombinant Mouse GABARAP Protein Pre-coupled Magnetic Beads HEK293
Rat GABARAP-2440R Recombinant Rat GABARAP Protein Mammalian Cell His
Rat GABARAP-2096R Recombinant Rat GABARAP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GABARAP-2096R-B Recombinant Rat GABARAP Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GABARAP-1786R Recombinant Rhesus monkey GABARAP Protein, His-tagged Mammalian Cell His
Rhesus Macaque GABARAP-1607R-B Recombinant Rhesus Macaque GABARAP Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GABARAP-1607R Recombinant Rhesus Macaque GABARAP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GABARAP Related Articles
  • GABARAP Related Research Area

GABARAP involved in several pathways and played different roles in them. We selected most pathways GABARAP participated on our site, such as Cellular responses to stress, FoxO signaling pathway, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABARAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cellular responses to stressBMI1B;HMGA1-RS1;HIST1H1B;HIST1H1D;PHC1;HIF1AL;HSPA14;ULK1A;C7orf59
FoxO signaling pathwaySIRT1;FOXO4;PIK3R2;SOS1;SLC2A4;PTENA;BCL6A;IL7R;EGFRA
GABAergic synapseGNG4;GABRP;GNB1;SLC6A1;GABRB1;GNB2;SLC6A13;GAD2;PRKACB
MacroautophagyATG101;WIPI1;RB1CC1;AMBRA1B;WIPI2;MAP1LC3B;ATG9B;DYNLL2A;ATG9A
Regulation of autophagyIFNA21;ATG13;IFNA7;IFNA14;INS1;IFNA10;ATG10;PRKAA1;IFNA17
Senescence and AutophagyCREG1;RB1CC1;SLC39A2;AMBRA1;IGFBP7;GABARAPL2;LC3;MAP1LC3B;UVRAG

GABARAP has several biochemical functions, for example, GABA receptor binding, beta-tubulin binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GABARAP itself. We selected most functions GABARAP had, and list some proteins which have the same functions with GABARAP. You can find most of the proteins on our site.

Function Related Protein
GABA receptor bindingMAF1;GABRB1;GABARAP;PLCL2;AKAP5;GABRA5;GABARAPL1;ARFGEF2;PPP2CA
beta-tubulin bindingSNCA;PDCD5;PEX14;GABARAP;ADNP;MAP1S;VAPB;CASC1;HTT
microtubule bindingPRNP;KIF11;S100A9;NDE1;HOOK3;KATNB1;TPPP;CASC1;SKA1
protein bindingCST9L;FADD;UBE2L6;LY96;FAM19A4;MTSS1;DIXDC1;SKAP2;PRKAB2
ubiquitin protein ligase bindingTRIB2;ARIH1;FANCL;TUBA1B;CUL3B;CUL1;RPA3;RELA;HSPD1

GABARAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABARAP here. Most of them are supplied by our site. Hope this information will be useful for your research of GABARAP.

SQSTM1; CALR; NBR1; ATG7

Marcial, HS; Suga, K; et al. Molecular cloning and localization of GABA(A) receptor-associated protein in the rotifer Brachionus plicatilis. INTERNATIONAL REVIEW OF HYDROBIOLOGY 99:188-197(2014).
Zsuzsanna, K; Patricia, P; et al. The stiff-person syndrome: a brief review and report of two cases. ORVOSI HETILAP 154:1984-1990(2013).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
What are the mechanisms by which GABARAP modulates protein aggregation and degradation in cells? 06/09/2022

GABARAP contributes to protein aggregation and degradation processes, crucial in maintaining cellular health.

How does GABARAP influence the trafficking and surface expression of GABA receptors? 01/09/2022

GABARAP impacts GABA receptor trafficking and surface expression, affecting receptor availability and signaling.

What is the impact of GABARAP on immune cell function and inflammatory responses? 07/07/2021

GABARAP plays a role in immune cell functioning and modulates inflammatory responses.

How does GABARAP participate in the process of autophagy and cellular homeostasis? 02/08/2021

GABARAP is involved in autophagy, aiding in the degradation and recycling of cellular components for homeostasis.

How does GABARAP contribute to the pathophysiology of neurological disorders, such as Alzheimer's disease? 04/30/2020

GABARAP is linked to the pathology of neurological disorders, potentially affecting protein aggregation and neuronal function.

What role does GABARAP play in neuronal signaling and the regulation of GABAergic synapses? 05/31/2018

GABARAP regulates neuronal signaling, particularly at GABAergic synapses, influencing neurotransmission.

How do alterations in GABARAP expression or function affect cancer cell growth and survival? 03/19/2018

Changes in GABARAP expression influence cancer cell behavior, impacting growth, survival, and responsiveness to therapy.

Customer Reviews (3)

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Reviews
09/10/2020

    Precise protein quantification, fundamental for our studies' accuracy.

    08/20/2020

      Efficient protein purification, consistent yields, cost-effective service.

      05/15/2020

        Dependable peptide synthesis, accelerates our peptide-based projects.

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