|Official Full Name||GABA(A) receptor-associated protein|
|Background||Gamma-aminobutyric acid A receptors (GABA(A) receptors) are ligand-gated chloride channels that mediate inhibitory;neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its;N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This;protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.|
|Synonyms||GABARAP; GABA(A) receptor-associated protein; gamma-aminobutyric acid receptor-associated protein; ATG8A; MM46; GABARAP-a; FLJ25768; MGC120154; MGC120155|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GABARAP involved in several pathways and played different roles in them. We selected most pathways GABARAP participated on our site, such as Cellular responses to stress, FoxO signaling pathway, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABARAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cellular responses to stress||HIST2H3C; CABIN1; RB1CC1; LAMTOR2; RAD50; HSPA13; EGLN2; LAMTOR1; CBX8B; HIST1H1E|
|FoxO signaling pathway||INSRA; CCNG2; TGFBR1B; AKT3A; FOXO4; MAPK12A; GADD45AA; IGF1RA; EGFRA; GADD45B|
|GABAergic synapse||GNG7; GABRG3; GABRD; PRKCA; GABBR1; GNG4; GABRB3; GNAI2; SLC38A5; PRKCG|
|Macroautophagy||AMBRA1B; DYNLL2A; ATG7; WDR45; LC3; ATG4A; GABARAP; AMBRA1A; RB1CC1; DYNLL2B|
|Regulation of autophagy||ATG14; IFNA13; ATG7; INS2; BECN1; IFNA16; IFNA3; INS; ULK2; GABARAPA|
|Senescence and Autophagy||SLC39A2; LC3; MAP1LC3C; SLC39A3; IGFBP5; CREG1; MAP1LC3B; UVRAG; GABARAPL2; GABARAP|
GABARAP has several biochemical functions, for example, GABA receptor binding, beta-tubulin binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GABARAP itself. We selected most functions GABARAP had, and list some proteins which have the same functions with GABARAP. You can find most of the proteins on our site.
|GABA receptor binding||PLCL2; GABARAPL2; GABRA5; ARFGEF2; PLCL1; GABARAPA; AKAP5; JAKMIP1; GABRG1; GABRB1|
|beta-tubulin binding||IFT74; NDEL1; VAPB; CCT5; HDAC6; AKAP1; TBCD; FGF13; PIFO; SERPINB1A|
|microtubule binding||CHP; KCNH2A; GABARAP; REEP1; PPP5C; GCAP14; MAPRE2; KATNB1; ARL3; MTAP6|
|protein binding||SMC6; GPR177; ARFGAP3; ZCCHC10; KTI12; PPP4R2; TMPO; SIKE1; CAMKK1; BRMS1|
|ubiquitin protein ligase binding||TRAF1; HDAC6; TPI1; MID1; PRKAR2B; NAE1; YOD1; NFKBIA; CUL1A; MDM2|
GABARAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABARAP here. Most of them are supplied by our site. Hope this information will be useful for your research of GABARAP.
SQSTM1; CALR; NBR1; ATG7