Recombinant Human GABARAP Protein, His-tagged Protein, Biotinylated

• Cat.No.: GABARAP-579H
• Product Overview: Recombinant Human GABARAP (Accession # NP_009209), fused with an N-terminal 6-His tag, was produced in E. coli. This protein has been modified with biotin via primary amine coupling.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: Recombinant Human GABARAP has a calculated MW of 16.3 kDa.
• Purity: >95% by PAGE
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: GABARAP GABA(A) receptor-associated protein [ Homo sapiens ]
• Official Symbol: GABARAP
• Synonyms: GABARAP; GABA(A) receptor-associated protein; gamma-aminobutyric acid receptor-associated protein; ATG8A; MM46; GABARAP-a; FLJ25768; MGC120154; MGC120155
• Gene ID: 11337
• mRNA Refseq: NM_007278
• Protein Refseq: NP_009209
• MIM: 605125
• UniProt ID: O95166
• Chromosome Location: 17p13.1

Reviews

09/10/2020

Precise protein quantification, fundamental for our studies' accuracy.

08/20/2020

Efficient protein purification, consistent yields, cost-effective service.

05/15/2020

Dependable peptide synthesis, accelerates our peptide-based projects.

Q&As

What are the mechanisms by which GABARAP modulates protein aggregation and degradation in cells?

GABARAP contributes to protein aggregation and degradation processes, crucial in maintaining cellular health.

How does GABARAP influence the trafficking and surface expression of GABA receptors?

GABARAP impacts GABA receptor trafficking and surface expression, affecting receptor availability and signaling.

What is the impact of GABARAP on immune cell function and inflammatory responses?

GABARAP plays a role in immune cell functioning and modulates inflammatory responses.

How does GABARAP participate in the process of autophagy and cellular homeostasis?

GABARAP is involved in autophagy, aiding in the degradation and recycling of cellular components for homeostasis.

How does GABARAP contribute to the pathophysiology of neurological disorders, such as Alzheimer's disease?

GABARAP is linked to the pathology of neurological disorders, potentially affecting protein aggregation and neuronal function.

What role does GABARAP play in neuronal signaling and the regulation of GABAergic synapses?

GABARAP regulates neuronal signaling, particularly at GABAergic synapses, influencing neurotransmission.

How do alterations in GABARAP expression or function affect cancer cell growth and survival?

Changes in GABARAP expression influence cancer cell behavior, impacting growth, survival, and responsiveness to therapy.