Recombinant Human GABA(A) Receptor-associated Protein

• Cat.No.: GABARAP-1010H

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: N-terminal GST tagged full-length GABARAP. GABARAP is essential for correct delivery of newly senthesized or recycled GABA type A receptor molecules to the postsynaptic membrane neurons. GABARAP has been expressed as a fusion protein with GST allowing expression in E. coli and purification by affinity chromatography. The native GST-GABARAP is the ideal tool for in vitro/in vivo investigations of the behaviour of cellular prions. It may be used for protein-protein interaction studies as well as for in vitro/in vivo conversion studies. The GST-tag facilitates the protein's application in typical GST pull-down assays.
• Form: Liquid. Supplied in 50 mM Tris-HCl pH 7.5 and 150 mM NaCl.
• Purity: ≥90% by SDS-PAGE.
• Usage: For in vitro use only.
• Storage: Quality guaranteed for 12 months store at - 80°C. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: GABARAP GABA(A) receptor-associated protein [ Homo sapiens ]
• Synonyms: GABARAP; GABA(A) receptor-associated protein; MM46; FLJ25768; MGC120154; MGC120155; Gamma-aminobutyric acid receptor-associated protein;FLC3B
• Gene ID: 11337
• mRNA Refseq: NM_007278
• Protein Refseq: NP_009209
• MIM: 605125
• UniProt ID: O95166
• Chromosome Location: 17
• Pathway: Regulation of autophagy
• Function: GABA receptor binding; beta-tubulin binding; microtubule binding; protein binding